Human brains vary across people and over time; such variation is not yet understood in
cellular terms. Here we describe a relationship between people's cortical neurons and …

The mammalian cerebrum performs high-level sensory perception, motor control and
cognitive functions through highly specialized cortical and subcortical structures. Recent …

BackgroundMost studies underline the contribution of heritable factors for psychiatric
disorders. However, heritability estimates depend on the population under study, diagnostic …

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental psychiatric
disorder characterized by deficits in attention and hyperactivity-impulsivity. These symptoms …

Importance Psychiatric traits associated with categorically defined psychiatric disorders are
heritable and present to varying degrees in the general population. It is commonly assumed …

Identification of risk variants for neuropsychiatric diseases within enhancers underscores the
importance of understanding population-level variation in enhancer function in the human …

Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with a
complex symptomatology, and core symptoms as well as functional impairment often persist …

Objective To investigate, by systematically reviewing the literature, whether the attention-
deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) associates with ADHD and …

Attention deficit/hyperactivity disorder (ADHD) is a debilitating disorder and most research
therefore focuses on its deficits and its treatment. Research on the potential positive sides of …