Epilepsy is a serious neurological disorder characterized by abnormal, recurrent, and
synchronous discharges in the brain. Long-term recurrent seizure attacks can cause serious …

The function of guanine-based purines (GBPs) is mostly attributed to the intracellular
modulation of heteromeric and monomeric G proteins. However, extracellular effects of …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that currently affects
36 million people worldwide with no effective treatment available. Development of AD …

Age-related macular degeneration is a major cause of vision impairment in the Western
world among people of 55 years and older. Recently we have shown that autophagy is …

Soft tissue defects or pathologies frequently necessitate the use of biomaterials that provide
the volume required for subsequent vascularization and tissue formation as autrografts are …

Since the middle of the twentieth century, the use of dyes has become more common in
every food group as well as in the pharmaceutical, textile and cosmetic industries. Azo dyes …

Glial cells are involved in multiple cerebral functions that profoundly influence brain tissue
viability during ischemia, and astrocytes are the main source of extracellular purines as …

In the aging population, lower urinary tract (LUT) dysfunction is common and often leads to
storage and voiding difficulties classified into overlapping symptom syndromes. Despite …

Asthma is one of the most common respiratory diseases. Lack of response or poor
adherence to corticosteroids demands the development of new drug candidates for asthma …

Guanosine and adenosine are important neuromodulators in the brain and work in
cooperation to mitigate the effects of stroke, traumatic injury, and other neurological events …