Bone fractures and segmental bone defects are a significant source of patient morbidity and
place a staggering economic burden on the healthcare system. The annual cost of treating …

Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

There is enormous global anticipation for stem cell-based therapies that are safe and
effective. Numerous pre-clinical studies present encouraging results on the therapeutic …

Regenerative medicine is a burgeoning field that is important to combat challenging
diseases and functional impairments. Compared with traditional cell therapies with evident …

Cell sheet engineering has been developed as an alternative approach to improve
mesenchymal stem cell‐mediated tissue regeneration. In this study, we found that vitamin C …

Mesenchymal stem cell derived extracellular matrix (MSC-ECM) is a natural biomaterial with
robust bioactivity and good biocompatibility, and has been studied as a scaffold for tissue …

OBJECTIVE: This study focused on the characterization of stem cells from human exfoliated
deciduous teeth (SHED) in comparison with dental pulp stem cells (DPSCs) to certify SHED …

The lack of effective strategies to produce vascularized 3D bone transplants in vitro,
hampers the development of thick-constructed bone, limiting the translational of lab-based …

The scaffold‐free cell‐sheet technique plays a significant role in stem‐cell‐based
regeneration. Furthermore, growth factors are known to direct stem cell differentiation and …

Mesenchymal stem cells (MSCs) are multipotent cells capable of proliferating and
differentiating into several lineages. In regenerative medicine, their potential as a resource …