Betaine is an essential osmolyte and source of methyl groups and comes from either the diet
or by the oxidation of choline. Its metabolism methylates homocysteine to methionine, also …

Impaired fertility during periods of heat stress is the culmination of numerous physiological
responses to heat stress, ranging from reduced estrus expression and altered follicular …

Recent findings show that zinc is an important factor necessary for regulating the meiotic cell
cycle and ovulation. However, the role of zinc in promoting oocyte quality and …

DNA methylation is a key epigenetic modification which is essential for normal embryonic
development. Major epigenetic reprogramming takes place during gametogenesis and in …

One-carbon (1C) metabolism consists of an integrated series of metabolic pathways that
include the folate cycle and methionine remethylation and trans-sulfuration pathways. Most …

Micro RNA‐29b (miR‐29b) is a member of the miR‐29 family, which targets DNA
methyltransferases (DNMT s) and ten eleven translocation enzymes (TET s), thereby …

The follicle is an important unit for the synthesis of steroid hormones and the oocyte
development and maturation in mammals. However, the effect of methionine supply on …

The embryonic pattern of global DNA methylation is first established in the inner cell mass
(ICM) of the mouse blastocyst. The methyl donor S‐adenosylmethionine (SAM) is produced …

Choline is a precursor of acetylcholine, phosphatidylcholine, and the methyl-donor betaine.
Reports indicate that supplementation with rumen-protected choline improves postpartum …

One-carbon (1C) metabolism provides methyl groups for the synthesis and/or methylation of
purines and pyrimidines, biogenic amines, proteins, and phospholipids. Our understanding …