Spontaneous solute and solvent permeation through membranes is of vital importance to
human life, be it gas exchange in red blood cells, metabolite excretion, drug/toxin uptake, or …

NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

Intracellular signaling mechanisms in red blood cells (RBCs) involve various protein kinases
and phosphatases and enable rapid adaptive responses to hypoxia, metabolic …

Aquaporins (AQPs) are channel-forming integral membrane proteins that facilitate the
movement of water and many other small molecules. Compared to animals, plants contain a …

The results of NMR, and especially pulsed field gradient NMR (PFG NMR) investigations,
are summarized. Pulsed field gradient NMR technique makes it possible to investigate …

Purpose To determine the intracellular water preexchange lifetime, τi, the “average
residence time” of water, in the intracellular milieu of neurons and astrocytes. The …

Cryopreservation is a key step for the effective delivery of many cell therapies and for the
maintenance of biological materials for research. The preservation process must be carefully …

Plasma and blood osmolality values show interspecies differences and are strictly regulated.
The effect of these factors also has an influence on microrheological parameters, such as …

Water transport across cell membranes can be measured non-invasively with diffusion NMR.
We present a method to quantify the intracellular lifetime of water in cell suspensions with …

The water exchange lifetime (τ i) through red blood cell (RBC) membranes can be measured
by analyzing the water protons bi-exponential T 1 and T 2 curves when RBCs are …