Sirtuins are a class of NAD+-dependent deacetylases having beneficial health effects. This
extensive review describes the numerous intracellular actions of the seven mammalian …

Background: Today, cancer is the leading cause of death. It appears that using large
amounts of natural resources reduces the damaging consequences of cancer therapy. Over …

Resveratrol has been shown to possess multiple pharmacological activities including anti-
tumor, anti-inflammation and immunomodulation, and participates in the regulation of the NF …

Inflammatory bowel disease (IBD) is known to significantly increase the risk for development
of colorectal cancer (CRC), suggesting inflammation and cancer development are closely …

The interaction between tumor cells and the tumor microenvironment (TME) is an important
process for the development of tumor malignancy. Modulation of paracrine cross-talk could …

Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer
mortality in the world. Many natural products and traditional herbal medicines have been …

Scope Colitis, an inflammatory bowel disease, is associated with aberrant regulation of the
colonic mucosal immune system. Resveratrol, a natural plant product, has been found to …

BACKGROUND AND PURPOSE Sirtuin 6 (SIRT6) is involved in regulation of glucose and
fat metabolism. However, its possible contribution to cardiac dysfunction remains to be …

Objectives This study aimed at investigating the effect of the systemic administration of
resveratrol (RESV) on oxidative stress during experimental periodontitis in rats subjected to …

Resveratrol, a naturally occurring polyphenol has received significant attention as a potent
anti-inflammatory agent. Inflammatory bowel disease (IBD) is a chronic intestinal …