Nuclear factor kappa B (NF-κB), an oncogenic signaling factor plays a critical role in the
development and progression of various cancers. The objective of this study was to …

Cancer is a multifactorial disorder that induces mortality worldwide, and the colorectal type is
the third most common cancer globally. Resveratrol (RSV) is a natural compound with an …

Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene)(RES) is a naturally-derived
phytoestrogen found in the skins of red grapes and berries and has potential as a novel and …

We explored the activity of SIRT1 activators (SRT501 and SRT2183) alone and in
combination with panobinostat in a panel of malignant lymphoid cell lines in terms of …

Abstract Background Aquaporin 3 (AQP3) is the predominant aquaporin in the skin and is
overexpressed in hyperplastic epidermal disorders. Upregulation of AQP3 contributes to …

Ovarian follicular atresia is characterized by granulosa cell apoptosis, however, the exact
mechanism is still unclear. Sirtuin 1 (SIRT1) is a NAD+-dependent deacetylase, which is …

Dietary consumption of fruit, vegetables, fish, and olive oil has been demonstrated to exert
beneficial effects on human health. This finding may be due to the high content of …

Cardio-oncology is a clinical/scientific discipline which aims to prevent and/or treat
cardiovascular diseases in cancer patients. Although a large number of cancer treatments …

Mauritius Island possesses unique plant biodiversity with a potential reservoir of biologically
active compounds of pharmacological interest. In the current study, we investigated …

Immunotherapy with high-dose interleukin-2 (HDIL-2) is an effective treatment for patients
with metastatic melanoma and renal cell carcinoma. However, it is accompanied by severe …