Polycyclic aromatic hydrocarbon and its effects on human health: An overeview

MA Mallah, L Changxing, MA Mallah, S Noreen, Y Liu… - Chemosphere, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are a class of chemicals of considerable
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

[HTML][HTML] The aryl hydrocarbon receptor as a target of environmental stressors–Implications for pollution mediated stress and inflammatory responses

CFA Vogel, LS Van Winkle, C Esser… - Redox biology, 2020 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

[HTML][HTML] The toxicological mechanisms of environmental soot (black carbon) and carbon black: focus on oxidative stress and inflammatory pathways

R Niranjan, AK Thakur - Frontiers in immunology, 2017 - frontiersin.org
The environmental soot and carbon blacks (CBs) cause many diseases in humans, but their
underlying mechanisms of toxicity are still poorly understood. Both are formed after the …

Endocrine‐disrupting chemicals: associated disorders and mechanisms of action

S De Coster, N Van Larebeke - Journal of environmental and …, 2012 - Wiley Online Library
The incidence and/or prevalence of health problems associated with endocrine‐disruption
have increased. Many chemicals have endocrine‐disrupting properties, including bisphenol …

[HTML][HTML] Activation of proinflammatory responses in cells of the airway mucosa by particulate matter: oxidant-and non-oxidant-mediated triggering mechanisms

J Øvrevik, M Refsnes, M Låg, JA Holme, PE Schwarze - Biomolecules, 2015 - mdpi.com
Inflammation is considered to play a central role in a diverse range of disease outcomes
associated with exposure to various types of inhalable particulates. The initial mechanisms …

Cell death pathways of particulate matter toxicity

MS Peixoto, MF de Oliveira Galvão, SRB de Medeiros - Chemosphere, 2017 - Elsevier
Humans are exposed to various complex mixtures of particulate matter (PM) from different
sources. Long-term exposure to high levels of these particulates has been linked to a …

[HTML][HTML] Cell cycle alterations induced by urban PM2. 5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved

E Longhin, JA Holme, KB Gutzkow, VM Arlt… - Particle and fibre …, 2013 - Springer
Background This study explores and characterizes cell cycle alterations induced by urban
PM2. 5 in the human epithelial cell line BEAS-2B, and elucidates possible mechanisms …

[HTML][HTML] Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring

JE Rager, MJ Strynar, S Liang, RL McMahen… - Environment …, 2016 - Elsevier
There is a growing need in the field of exposure science for monitoring methods that rapidly
screen environmental media for suspect contaminants. Measurement and analysis …

[HTML][HTML] Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles

JA Holme, BC Brinchmann, M Refsnes, M Låg… - Environmental …, 2019 - Springer
Air pollution is the most important environmental risk factor for disease and premature death,
and exposure to combustion particles from vehicles is a major contributor. Human …