Resveratrol as a tumor-suppressive nutraceutical modulating tumor microenvironment and malignant behaviors of cancer

Y Han, HA Jo, JH Cho, DN Dhanasekaran… - International journal of …, 2019 - mdpi.com
Tumor-suppressive effects of resveratrol have been shown in various types of cancer.
However, regulation of tumor microenvironment by resveratrol is still unclear. Recent …

Targeting extracellular matrix through phytochemicals: a promising approach of multi-step actions on the treatment and prevention of cancer

D Liang, L Liu, Y Zhao, Z Luo, Y He, Y Li… - Frontiers in …, 2023 - frontiersin.org
Extracellular matrix (ECM) plays a pivotal and dynamic role in the construction of tumor
microenvironment (TME), becoming the focus in cancer research and treatment. Multiple cell …

Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats

HF Zhao, N Li, Q Wang, XJ Cheng, XM Li, TT Liu - Neuroscience, 2015 - Elsevier
Our previous studies demonstrated resveratrol (Res) administration protected Alzheimer's
disease (AD) rats from developing memory decline by anti-oxidation. Beta-amyloid peptide 1 …

Association of resveratrol with the suppression of TNF-α/NF-kB/iNOS/HIF-1α axis-mediated fibrosis and systemic hypertension in thioacetamide-induced liver injury

HA Ebrahim, SS Kamar, MA Haidara, NSA Latif… - Naunyn-Schmiedeberg's …, 2022 - Springer
Chronic liver injury can lead to hepatic failure and the only available method of treatment
would be liver transplantation. The link between inflammation (TNF-α), nuclear factor-kappa …

Uncovering the mechanism of resveratrol in the treatment of diabetic kidney disease based on network pharmacology, molecular docking, and experimental validation

S Chen, B Li, L Chen, H Jiang - Journal of Translational Medicine, 2023 - Springer
Background Diabetic kidney disease (DKD) has been the leading cause of chronic kidney
disease in developed countries. Evidence of the benefits of resveratrol (RES) for the …

An update on current and future treatment options for chondrosarcoma

IJ MacDonald, CY Lin, SJ Kuo, CM Su… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Human chondrosarcomas (CS; a malignant cartilage-forming bone tumor)
respond poorly to chemotherapy and radiation treatment, resulting in high morbidity and …

Efficacy of resveratrol to supplement oral nifedipine treatment in pregnancy-induced preeclampsia

J Ding, Y Kang, Y Fan, Q Chen - Endocrine connections, 2017 - ec.bioscientifica.com
Objective Preeclampsia (PE) is a complication affecting pregnant women worldwide, which
usually manifests as severe maternal hypertension. Resveratrol (RESV), a naturally existing …

Interplay of Vitamin D and SIRT1 in Tissue-Specific Metabolism—Potential Roles in Prevention and Treatment of Non-Communicable Diseases Including Cancer

Z Nemeth, A Patonai, L Simon-Szabó… - International Journal of …, 2023 - mdpi.com
The importance of the prevention and control of non-communicable diseases, including
obesity, metabolic syndrome, type 2 diabetes, cardiovascular diseases, and cancer, is …

Resveratrol improves delayed r‐tPA treatment outcome by reducing MMP s

J Chen, Q Bai, Z Zhao, H Sui… - Acta Neurologica …, 2016 - Wiley Online Library
Objectives Although recombinant tissue plasminogen activator (r‐tPA) is currently the most
effective treatment for brain ischemic stroke, the 3‐h narrow therapeutic windows severely …

Recent advances in gossypol derivatives and analogs: a chemistry and biology view

Y Lu, J Li, CE Dong, J Huang, HB Zhou… - Future Medicinal …, 2017 - Future Science
Gossypol as a natural occurring polyphenol has been studied in a wide range of therapeutic
contexts for a long time. The chemical modifications on gossypol were limited due to the …