[HTML][HTML] Cross-talk mechanism between endothelial cells and hepatocellular carcinoma cells via growth factors and integrin pathway promotes tumor angiogenesis …

T Feng, H Yu, Q Xia, Y Ma, H Yin, Y Shen, X Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tumor angiogenesis plays a central role in the development and metastasis of
hepatocellular carcinoma. Cancer cells secrete angiogenic factors to recruit vascular …

Toll-like receptor 4 signaling promotes invasion of hepatocellular carcinoma cells through MKK4/JNK pathway

YQ Dong, CW Lu, L Zhang, J Yang, W Hameed… - Molecular …, 2015 - Elsevier
Abstract Toll-like receptor (TLR) 4-mediated signaling has been shown to be important to
cell survival, invasion and metastasis in a variety of cancers. The present study aimed to …

Sphingosine‐1‐phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR‐101 …

CH Tsai, DY Yang, CY Lin, TM Chen… - Molecular …, 2017 - Wiley Online Library
Chondrosarcoma is the second most common primary malignancy form of bone cancer,
exhibiting resistance to chemotherapy and radiation therapy as well as developing high …

Protective effect of resveratrol against nigrostriatal pathway injury in striatum via JNK pathway

D Li, N Liu, L Zhao, L Tong, H Kawano, HJ Yan, HP Li - Brain research, 2017 - Elsevier
Nigrostriatal pathway injury is one of the traumatic brain injury models that usually lead to
neurological dysfunction or neuron necrosis. Resveratrol-induced benefits have recently …

Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity

M Tauro, A Laghezza, F Loiodice… - Journal of Enzyme …, 2016 - Taylor & Francis
New catechol-containing chemical entities have been investigated as matrix
metalloproteinase inhibitors as well as antioxidant molecules. The combination of the two …

[HTML][HTML] Resveratrol Microencapsulation into Electrosprayed Polymeric Carriers for the Treatment of Chronic, Non-Healing Wounds

A De Pieri, K Ocorr, K Jerreld, M Lamoca, W Hitzl… - Pharmaceutics, 2022 - mdpi.com
Chronic, non-healing wounds represent a challenging socio-economic burden, demanding
innovative approaches for successful wound management. Resveratrol (RSV) represents a …

[HTML][HTML] Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo

J Mota, R Direito, J Rocha, J Fernandes… - International Journal of …, 2021 - mdpi.com
Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) are regarded as important clinical
targets due to their nodal-point role in inflammatory and oncological diseases. Here, we …

[HTML][HTML] Identification of medicinal compounds as potential inhibitors for mutated isocitrate dehydrogenases against chondrosarcoma

FH Shah, SJ Kim - Saudi Journal of Biological Sciences, 2022 - Elsevier
Chondrosarcoma is the third most common cartilaginous bone tumour that is insusceptible
to radio-and chemotherapy and it is inclined to metastasis. These resistant qualities are …

Resveratrol reduces matrix metalloproteinases and alleviates intrahepatic cholestasis of pregnancy in rats

Z Chen, L Hu, M Lu, Z Shen - Canadian journal of physiology …, 2016 - cdnsciencepub.com
Intrahepatic cholestasis of pregnancy (ICP) is a severe liver disorder occurring specifically in
pregnancy, and matrix metalloproteinase (MMP)-2 and MMP-9 were found to be elevated in …

Targeting protein kinases to reverse multidrug resistance in sarcoma

H Chen, J Shen, E Choy, FJ Hornicek, Z Duan - Cancer treatment reviews, 2016 - Elsevier
Sarcomas are a group of cancers that arise from transformed cells of mesenchymal origin.
They can be classified into over 50 subtypes, accounting for approximately 1% of adult and …