Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases

MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …

Recent advances in quinazolinones as an emerging molecular platform for luminescent materials and bioimaging

Z Xing, W Wu, Y Miao, Y Tang, Y Zhou… - Organic Chemistry …, 2021 - pubs.rsc.org
The quinazolinone skeleton is a common structure found in natural alkaloids and synthetic
drugs. In recent years, some quinazolinone derivatives have been found to exhibit good …

Imidazopyridine-based thiazole derivatives as potential antidiabetic agents: synthesis, in vitro bioactivity, and in silico molecular modeling approach

R Hussain, W Rehman, S Khan, A Maalik, M Hefnawy… - Pharmaceuticals, 2023 - mdpi.com
A new series of thiazole derivatives (4a-p) incorporating imidazopyridine moiety was
synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose …

Organoruthenium-bipyridyl complexes–A platform for diverse chemistry and applications

C Pandya, A Sivaramakrishna - Coordination Chemistry Reviews, 2024 - Elsevier
The increasing impact of organometallic complexes of group 8–10 metals academically and
industrially over the years demonstrates remarkable progress in harvesting useful reagents …

Ultrasound-assisted transition-metal-free catalysis: a sustainable route towards the synthesis of bioactive heterocycles

B Borah, LR Chowhan - RSC advances, 2022 - pubs.rsc.org
Heterocycles of synthetic and natural origin are a well-established class of compounds
representing a broad range of organic molecules that constitute over 60% of drugs and …

A comprehensive survey upon diverse and prolific applications of chitosan-based catalytic systems in one-pot multi-component synthesis of heterocyclic rings

H Mousavi - International Journal of Biological Macromolecules, 2021 - Elsevier
Heterocyclic compounds are among the most prestigious and valuable chemical molecules
with diverse and magnificent applications in various sciences. Due to the remarkable and …

Medicinal chemistry of quinazolines as analgesic and anti-inflammatory agents

MF Zayed - ChemEngineering, 2022 - mdpi.com
Quinazoline is an essential scaffold, known to be linked with various biological activities.
Some of the prominent biological activities of this system are analgesic, anti-inflammatory …

Functionalized triazines and tetrazines: Synthesis and applications

J Mondal, A Sivaramakrishna - Topics in Current Chemistry, 2022 - Springer
The molecules possessing triazine and tetrazine moieties belong to a special class of
heterocyclic compounds. Both triazines and tetrazines are building blocks and have …

Pyridyl Glycosyl Triazole/CuI-Mediated Domino/Tandem Synthesis of Quinazolinones

SK Singh, S Kumar, MS Yadav… - The Journal of Organic …, 2022 - ACS Publications
The glycosyl 1, 2, 3-triazoles are expediently accessible from readily available sugar-
derived glycosyl azide by utilizing modular CuAAC “Click Chemistry”, and the resulting …

Elucidating the role of novel halogenated hydroquinazolinone derivatives in mitigating copper corrosion in saline conditions: a joint assessment of experimental …

M Oubahou, M Rbaa, D Takky, Y Naimi… - Journal of Molecular …, 2023 - Elsevier
Corrosion of copper in marine environments represents a significant challenge,
necessitating the exploration of efficient corrosion inhibitors. This study probes the efficacy of …