[HTML][HTML] Van Gogh-like 2 is essential for the architectural patterning of the mammalian biliary tree
M Raab, E Christodoulou, R Krishnankutty… - Journal of …, 2024 - Elsevier
Background & Aims In the developing liver, bipotent epithelial progenitor cells undergo
lineage segregation to form hepatocytes, which constitute the bulk of the liver parenchyma …
lineage segregation to form hepatocytes, which constitute the bulk of the liver parenchyma …
Integrins in biliary injury and fibrosis
JR Schaub, JY Chen, SM Turner - Current Opinion in …, 2024 - journals.lww.com
While all members of the same family of proteins, integrins have diverse roles in the
pathogenesis of biliary disease. Targeting one or multiple of these integrins may slow or halt …
pathogenesis of biliary disease. Targeting one or multiple of these integrins may slow or halt …
[HTML][HTML] Cross-Species Insights into Autosomal Dominant Polycystic Kidney Disease: Provide an Alternative View on Research Advancement
J Luo, Y Zhang, S Jayaprakash, L Zhuang… - International Journal of …, 2024 - mdpi.com
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a prevalent hereditary disorder
that affects the kidneys, characterized by the development of an excessive number of fluid …
that affects the kidneys, characterized by the development of an excessive number of fluid …
[HTML][HTML] Epigenetic regulation of H3K27me3 in laying hens with fatty liver hemorrhagic syndrome induced by high-energy and low-protein diets
Y Cui, M Ru, Y Wang, L Weng, RA Haji, H Liang… - BMC genomics, 2024 - Springer
Background Fatty liver hemorrhagic syndrome (FLHS) in the modern poultry industry is
primarily caused by nutrition. Despite encouraging progress on FLHS, the mechanism …
primarily caused by nutrition. Despite encouraging progress on FLHS, the mechanism …
Understanding remodelling of bile ducts to promote polycystic liver disease
K Ray - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
New research has identified a key signalling axis linking transforming growth factor-β
(TGFβ), the extracellular matrix (ECM) and integrin in the promotion of bile duct remodelling …
(TGFβ), the extracellular matrix (ECM) and integrin in the promotion of bile duct remodelling …