Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

E Maniati, M Bossard, N Cook… - The Journal of …, 2011 - Am Soc Clin Investig
The majority of human pancreatic cancers have activating mutations in the KRAS proto-
oncogene. These mutations result in increased activity of the NF-κB pathway and the …

Gastric cancer stem cells: evidence, potential markers, and clinical implications

D Brungs, M Aghmesheh, KL Vine, TM Becker… - Journal of …, 2016 - Springer
Gastric cancer is a significant global health problem. It is the fifth most common cancer and
third leading cause of cancer-related death worldwide (Torre et al. in CA Cancer J Clin 65 …

Epigenetic Silencing of miR-490-3p Reactivates the Chromatin Remodeler SMARCD1 to Promote Helicobacter pylori–Induced Gastric Carcinogenesis

J Shen, Z Xiao, WKK Wu, MH Wang, KF To, Y Chen… - Cancer research, 2015 - AACR
Chromatin remodeling has emerged as a hallmark of gastric cancer, but the regulation of
chromatin regulators other than genetic change is unknown. Helicobacter pylori causes …

[HTML][HTML] Pathogenetic mechanisms in gastric cancer

J Shi, YP Qu, P Hou - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Gastric cancer (GC) is a major public health issue as the fourth most common cancer and
the second leading cause of cancer-related death. Recent advances have improved our …

[HTML][HTML] MicroRNA-143 suppresses gastric cancer cell growth and induces apoptosis by targeting COX-2

XL Wu, B Cheng, PY Li, HJ Huang, Q Zhao… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate the function of microRNA-143 (miR-143) in gastric cancer and explore
the target genes of miR-143. METHODS: A quantitative real-time reverse transcription …

[HTML][HTML] AURKA induces EMT by regulating histone modification through Wnt/β-catenin and PI3K/Akt signaling pathway in gastric cancer

X Liu, Z Li, Y Song, R Wang, L Han, Q Wang, K Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gastric cancer, a highly invasive and aggressive malignancy, is the third leading cause of
death from cancer worldwide. Genetic association studies have successfully revealed …

Genetic aspects of gastric cancer instability

P Hudler - The Scientific World Journal, 2012 - Wiley Online Library
Unravelling the molecular mechanisms underlying gastric carcinogenesis is one of the
major challenges in cancer genomics. Gastric cancer is a very complex and heterogeneous …

[HTML][HTML] Diabetes and gastric cancer: the potential links

CH Tseng, FH Tseng - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
This article reviews the epidemiological evidence linking diabetes and gastric cancer and
discusses some of the potential mechanisms, confounders and biases in the evaluation of …

Potential therapeutic effects of curcumin in gastric cancer

N Barati, AA Momtazi‐Borojeni… - Journal of cellular …, 2019 - Wiley Online Library
Despite recent advancements in understanding of the biology of gastric cancer, treatment of
patients with advanced gastric cancer remains a major problem. Among different type of …

Activation of the Notch1/STAT3/Twist signaling axis promotes gastric cancer progression

KW Hsu, RH Hsieh, KH Huang, A Fen-Yau Li… - …, 2012 - academic.oup.com
Gastric carcinoma is one of the most common malignancies and a lethal cancer in the world.
Notch signaling and transcription factors STAT3 (signal transducer and activator of …