The role of osteoclast energy metabolism in the occurrence and development of osteoporosis

W Da, L Tao, Y Zhu - Frontiers in endocrinology, 2021 - frontiersin.org
In recent decades, the mechanism underlying bone metabolic disorders based on energy
metabolism has been heavily researched. Bone resorption by osteoclasts plays an important …

Nutrition, physical activity, and dietary supplementation to prevent bone mineral density loss: a food pyramid

M Rondanelli, MA Faliva, GC Barrile, A Cavioni… - Nutrients, 2021 - mdpi.com
Bone is a nutritionally modulated tissue. Given this background, aim of this review is to
evaluate the latest data regarding ideal dietary approach in order to reduce bone mineral …

Vegan diet and bone health—results from the cross-sectional RBVD study

J Menzel, K Abraham, GI Stangl, PM Ueland, R Obeid… - Nutrients, 2021 - mdpi.com
Scientific evidence suggests that a vegan diet might be associated with impaired bone
health. Therefore, a cross-sectional study (n= 36 vegans, n= 36 omnivores) was used to …

Obesity, bone loss, and periodontitis: the interlink

P Zhao, A Xu, WK Leung - Biomolecules, 2022 - mdpi.com
Obesity and periodontitis are both common health concerns that have given rise to
considerable economic and societal burden worldwide. There are established negative …

Dual effects of lipid metabolism on osteoblast function

NS Alekos, MC Moorer, RC Riddle - Frontiers in Endocrinology, 2020 - frontiersin.org
The skeleton is a dynamic and metabolically active organ with the capacity to influence
whole body metabolism. This newly recognized function has propagated interest in the …

Regulation of osteoclast differentiation and activity by lipid metabolism

H Kim, B Oh, KH Park-Min - Cells, 2021 - mdpi.com
Bone is a dynamic tissue and is constantly being remodeled by bone cells. Metabolic
reprogramming plays a critical role in the activation of these bone cells and skeletal …

Fatty acids and oxylipins in osteoarthritis and rheumatoid arthritis—A complex field with significant potential for future treatments

AM Mustonen, P Nieminen - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review Osteoarthritis (OA) and rheumatoid arthritis (RA) are
characterized by abnormal lipid metabolism manifested as altered fatty acid (FA) profiles of …

The impact of a high fat diet on bones: potential mechanisms

J Qiao, Y Wu, Y Ren - Food & Function, 2021 - pubs.rsc.org
A high-fat diet (HFD) is defined as a diet that contains lipids that account for more than 30%
of the total energy intake, and current research has documented cases with intakes as high …

Gender-and age-associated differences in bone marrow adipose tissue and bone marrow fat unsaturation throughout the skeleton, quantified using chemical shift …

KM Beekman, M Regenboog, AJ Nederveen… - Frontiers in …, 2022 - frontiersin.org
Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with
osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is to …

Er-Xian decoction attenuates ovariectomy-induced osteoporosis by modulating fatty acid metabolism and IGF1/PI3K/AKT signaling pathway

Y Ma, J Hu, C Song, P Li, Y Cheng, Y Wang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Er-Xian decoction (EXD) is a traditional Chinese
medicine (TCM) formula used to treat osteoporosis (OP). However, the anti-OP mechanism …