A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …

Patients with cirrhosis and portal hypertension often develop complications from a variety of
organ systems leading to a multiple organ failure. The combination of liver failure and portal …

During the course of cirrhosis, there is a progressive deterioration of cardiac function
manifested by the disappearance of the hyperdynamic circulation due to a failure in heart …

This review aims at evaluating the existing evidence regarding post reperfusion syndrome,
providing a description of the pathophysiologic mechanisms involved and possible …

Liver transplantation has emerged as a highly efficient treatment for a variety of acute and
chronic liver diseases. However, organ shortage is becoming an increasing problem …

The use of renal resistive indices (RRIs) for the study of renal microcirculation has in the past
been proposed for the identification of renal organ damage or even to specifically identify …

Hepatic fibrosis is marked by activation of hepatic stellate cells (HSCs). Cholestatic injury
precedes liver fibrosis, and cholangiocytes interact with HSCs promoting fibrosis. Mast cells …

Patients suffering from liver cirrhosis (LC) frequently require non-hepatic abdominal surgery,
even before liver transplantation. LC is an important risk factor itself for surgery, due to the …

Bone marrow (BM) is a reservoir for immune and hematopoietic cells and critical for tissue
repair and regeneration. All of these functions are severely altered in cirrhosis. We …

Liver cirrhosis is associated with multiple vascular syndromes affecting almost all body
systems. Many of these syndromes are directly related to impaired liver function and …