While century old clinical reports document the periosteum's remarkable regenerative
capacity, only in the past decade have scientists undertaken mechanistic investigations of its …

The links between muscle and bone have been recently examined because of the
increasing number of patients with osteoporosis and sarcopenia. Myokines are skeletal …

Over the last four decades, bioarchaeology has experienced significant technical growth
and theoretical maturation. Early 21st century bioarchaeology may also be enhanced from a …

The clinical significance of sarcopenia and osteoporosis has increased with the increase in
the population of older people. Sarcopenia is defined by decreased muscle mass and …

Cortical bone structure is a crucial determinant of bone strength, yet for many years studies
of novel genes and cell signalling pathways regulating bone strength have focused on the …

Periosteum as an important component in the construct of bone is mainly responsible for
providing nourishment and regulating osteogenic differentiation. When bone defect …

Ciliary neurotrophic factor (CNTF) is the most extensively studied member of the cytokine
family that signal through intracellular chains of the gp130/LIFRβ receptor. The severe …

Bone renews itself and changes shape throughout life to account for the changing needs of
the body; this requires co-ordinated activities of bone resorbing cells (osteoclasts), bone …

Background Periosteum is a vascularized tissue membrane covering the bone surface and
plays a decisive role in bone reconstruction process after fracture. Various artificial …

Annual costs are enormous for musculoskeletal diseases such as osteoporosis and
sarcopenia and for bone and muscle injuries, costing billions annually in health care …