From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
T Efferth - Seminars in cancer biology, 2017 - Elsevier
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …
Artemisinins: pharmacological actions beyond anti-malarial
Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
Time to set the agenda for schistosomiasis elimination
D Rollinson, S Knopp, S Levitz, JR Stothard… - Acta tropica, 2013 - Elsevier
It is time to raise global awareness to the possibility of schistosomiasis elimination and to
support endemic countries in their quest to determine the most appropriate approaches to …
support endemic countries in their quest to determine the most appropriate approaches to …
[HTML][HTML] Repurposing drugs for the treatment and control of helminth infections
G Panic, U Duthaler, B Speich, J Keiser - International Journal for …, 2014 - Elsevier
Helminth infections are responsible for a considerable public health burden, yet the current
drug armamentarium is small. Given the high cost of drug discovery and development, the …
drug armamentarium is small. Given the high cost of drug discovery and development, the …
Jasmonate and abscisic acidactivated AaGSW1AaTCP15/AaORA transcriptional cascade promotes artemisinin biosynthesis in Artemisia annua
Artemisinin, a sesquiterpene lactone widely used in malaria treatment, was discovered in
the medicinal plant Artemisia annua. The biosynthesis of artemisinin is efficiently regulated …
the medicinal plant Artemisia annua. The biosynthesis of artemisinin is efficiently regulated …
The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use
KM Pfarr, AK Krome, I Al-Obaidi, H Batchelor… - Parasites & …, 2023 - Springer
In its 'Road map for neglected tropical diseases 2021–2030', the World Health Organization
outlined its targets for control and elimination of neglected tropical diseases (NTDs) and …
outlined its targets for control and elimination of neglected tropical diseases (NTDs) and …
[HTML][HTML] A new global strategy for the elimination of schistosomiasis
AGP Ross, TN Chau, MT Inobaya, RM Olveda… - International Journal of …, 2017 - Elsevier
Mass drug administration utilising a single oral dose of 40 mg/kg of praziquantel (PZQ) has
been endorsed and advocated by the World Health Organisation (WHO) for the global …
been endorsed and advocated by the World Health Organisation (WHO) for the global …
From the one health perspective: schistosomiasis japonica and flooding
SY Guo, L Li, LJ Zhang, YL Li, SZ Li, J Xu - Pathogens, 2021 - mdpi.com
Schistosomiasis is a water-borne parasitic disease distributed worldwide, while
schistosomiasis japonica localizes in the People's Republic of China, the Philippines, and a …
schistosomiasis japonica localizes in the People's Republic of China, the Philippines, and a …
Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis
L Monin, KL Griffiths, WY Lam, R Gopal… - The Journal of …, 2015 - Am Soc Clin Investig
Parasitic helminth worms, such as Schistosoma mansoni, are endemic in regions with a high
prevalence of tuberculosis (TB) among the population. Human studies suggest that helminth …
prevalence of tuberculosis (TB) among the population. Human studies suggest that helminth …
[PDF][PDF] Nobel Prize for artemisinin brings phytotherapy into the spotlight
T Efferth, S Zacchino, MI Georgiev, L Liu, H Wagner… - …, 2015 - artemisiavet.de
It is a great news for the entire scientific community dedicated to natural products that the
Nobel Prize in Physiology or Medicine 2015 was awarded by the Nobel Assembly at …
Nobel Prize in Physiology or Medicine 2015 was awarded by the Nobel Assembly at …