To date, the AP‐2 family of transcription factors comprises five members. Transcription factor
AP‐2beta (TFAP2B)/AP‐2β was first described in 1995. Several studies indicate a critical …

The TFAP2 family regulates gene expression during differentiation, development, and
organogenesis, and includes five homologs in humans. They all possess a highly conserved …

Lung adenocarcinoma (LUAD) is the predominant type of non-small lung cancer (NSCLC)
with strong invasive ability and poor prognosis. The drug resistance related genes are …

Background Ubiquitin-specific protease 22 (USP22), a putative cancer stem cell marker, is
frequently upregulated in cancers, and USP22 overexpression is associated with aggressive …

Background RNA modification, a major component of post-transcriptional modification, plays
an essential role in tumor initiation and progression. N4-acetylcytidine (ac4C) present in …

Transcription factor AP-2-alpha (Tfap2a) is an important sequence-specific DNA-binding
protein that can regulate the transcription of multiple genes by collaborating with inducible …

Members of the activator protein 2 (AP-2) transcription factor (TF) family are known to play a
role in both physiological processes and cancer development. The family comprises five …

Background: Dysfunction of endothelial cells links to microvascular rarefaction, reflecting the
pathogenesis of hypertension. Our previous studies found that miR-3656 reduces nitric …

The AP-2 family of transcription factors consist of DNA-binding proteins: AP-2α to AP-2ε.
Members and homologs of this family are also known in frogs, fish and invertebrates. These …

转录因子激活蛋白2γ (AP-2γ) 不仅在早期胚胎发育中调节着控制滋养外胚层细胞增殖和分化的
遗传程序, 还参与调控乳腺癌, 肺癌, 睾丸癌, 黑色素瘤及胰腺癌等多种肿瘤发展过程中的关键 …