Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

The purpose of this article is to review the suitability of the analytical and statistical
techniques that have thus far been developed to assess the dissolution behavior of particles …

Current pulmonary treatments against Pseudomonas aeruginosa infections in cystic fibrosis
(CF) lung suffer from deactivation of the drug and immobilization in thick and viscous …

An investigation for assessing pulmonary bioaccessibility of metals from reference materials
is presented using simulated lung fluids. The objective of this paper was to contribute to an …

Abstract The Biopharmaceutics Classification System (BCS), developed in the 1990s for oral
immediate release drugs, is utilized by R&D scientists and regulators to streamline product …

Abstract In 2003, the FIP Dissolution Working group published a position paper on
dissolution/drug release testing for special/novel dosage forms that represented the …

We investigated the feasibility of preparing high-potency tacrolimus dry powder for
inhalation using thin film freezing (TFF). We found that using ultra-rapid freezing can …

Pulmonary delivery of vasodilators is a promising alternative for the intravenous and oral
treatment of pulmonary arterial hypertension (PAH). The aim of this study was to design and …

Purpose The purpose of the study was initial evaluation of applicability of metal organic
framework (MOF) Fe-MIL-101-NH 2 as a theranostic carrier of antituberculous drug in terms …

Systemic administration of antifungal agents for the treatment of pulmonary aspergillosis is
limited by the poor lung deposition and severe adverse effects. In contrast, pulmonary …