Apheresis has been recognized both economically and therapeuticallyas a novel approach
for the treatment of inflammatory diseases, and certain others, which respond poorly to drug …

Patients with active inflammatory bowel disease (IBD) have elevated and activated myeloid
leucocytes which infiltrate the colonic mucosa in vast numbers. Myeloid leucocytes such as …

Active ulcerative colitis (UC) is characterized by activation and infiltration of granulocytes
and monocytes/macrophages into the colonic mucosa. The infiltrated leukocytes can cause …

Background & Aims: Active ulcerative colitis (UC) is characterized by infiltration of activated
granulocytes and monocytes/macrophages (GM) within the large bowel mucosa. GM are …

Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …

Corticosteroid therapy of ulcerative colitis (UC) is associated with frequent adverse side
effects and poor quality of life. Recently, adsorptive granulocyte and monocyte/macrophage …

Background/Aim: Active ulcerative colitis (UC) is often associated with increased peripheral
granulocytes and monocytes/macrophages which show activation behavior and prolonged …

Pyoderma gangrenosum (PG) is a rare, neutrophilic skin disease. For the purpose of
accurate diagnosis and proper treatment of PG, the Japanese clinical practice guidance for …

Granulocyte and monocyte adsorptive apheresis (GMA) using a column filled with cellulose
acetate (CA) beads (carriers) has been associated with a significant clinical efficacy in …

Abstract Background Active Crohn's disease (CD) is often associated with elevated levels of
platelets, granulocytes, and monocytes that are activated and resistant to apoptosis. The …