Bone remodeling is a continuous process that maintains the homeostasis of the skeletal
system, and it depends on the homeostasis between bone-forming osteoblasts and bone …

Osteoporosis is a metabolic disease characterized by decreased bone mineral density and
the destruction of bone microstructure, which can lead to increased bone fragility and risk of …

Osteoporosis is a metabolic skeletal disorder in which bone mass is depleted and bone
structure is destroyed to the degree that bone becomes fragile and prone to fractures …

Objective: Resveratrol has been confirmed to improve bone quality and delay osteoporosis,
but the mechanisms have not been thoroughly elucidated. In this report, we investigated the …

Bone metabolism consists of a balance between bone formation and bone resorption, which
is mediated by osteoblast and osteoclast activity, respectively. In order to ensure bone …

The ability of human periodontal ligament stem cells (PDLSCs) to differentiate into
osteoblasts is significant in periodontal regeneration tissue engineering. In this study, we …

Abstract Vacuolar ATPases (V-ATPases) play a critical role in regulating extracellular
acidification of osteoclasts and bone resorption. The deficiencies of subunit a3 and d2 of V …

Bone is a rigid and dynamic organ that continuously undergoes remodeling and repair. The
balance between osteoblastic bone formation and osteoclastic bone resorption is essential …

Bone is a complex tissue that undergoes constant remodeling to maintain homeostasis,
which requires coordinated multilineage differentiation and proper proliferation of …

Objectives To identify epigenetic and transcriptional factors controlling osteoclastogenesis
(OCG), that have been shown to play a role in the pathogenesis of skeletal diseases …