Recent miRNA research in asthma

R Sharma, A Tiwari, MJ McGeachie - Current allergy and asthma reports, 2022 - Springer
Abstract Purpose of Review The study of microRNA in asthma has revealed a vibrant new
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …

Potential Pathogenic Impact of Cow's Milk Consumption and Bovine Milk-Derived Exosomal MicroRNAs in Diffuse Large B-Cell Lymphoma

BC Melnik, R Stadler, R Weiskirchen… - International Journal of …, 2023 - mdpi.com
Epidemiological evidence supports an association between cow's milk consumption and the
risk of diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma …

Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages

N Yang, X Li - Biochemical Pharmacology, 2022 - Elsevier
Epigallocatechin gallate (EGCG) is an active catechin in green tea and has multiple
biological functions, such as anti-inflammation, anti-cancer, and immune regulation. This …

Lung adenocarcinoma cell-derived exosomes promote M2 macrophage polarization through transmission of miR-3153 to activate the JNK signaling pathway

L Xu, L Wang, R Yang, T Li, X Zhu - Human Molecular Genetics, 2023 - academic.oup.com
There is increasing evidence that exosome-mediated transmission of microRNAs helps to
connect tumor-associated macrophages and cancer cells, including lung adenocarcinoma …

Rosiglitazone ameliorated airway inflammation induced by cigarette smoke via inhibiting the M1 macrophage polarization by activating PPARγ and RXRα

H Feng, Y Yin, R Zheng, J Kang - International immunopharmacology, 2021 - Elsevier
Background Rosiglitazone, an exogenous ligand of PPARγ, plays an important anti-
inflammatory role during the inflammation caused by cigarette smoke (CS). CS exposure …

Role of obesity in inflammation and remodeling of asthmatic airway

H Shailesh, IA Janahi - Life, 2022 - mdpi.com
Obesity is considered as an important risk factor for the onset of asthma and plays a key role
in enhancing the disease's severity. Obese asthmatic individuals represent a distinct …

Coronavirus infection: An immunologists' perspective

JB De Sanctis, AH García, D Moreno… - … journal of immunology, 2021 - Wiley Online Library
Coronavirus infections are frequent viral infections in several species. As soon as the severe
acute respiratory syndrome (SARS) appeared in the early 2000s, most of the research …

Non-coding RNA regulation of macrophage function in asthma

C Tian, J Gao, L Yang, X Yuan - Cellular Signalling, 2023 - Elsevier
As a chronic respiratory disease, asthma is related to airway inflammation and remodeling.
Macrophages are regarded as main innate immune cells in the airway that exert various …

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation

Y Wang, W Xie, Y Feng, Z Xu, Y He… - International …, 2022 - spandidos-publications.com
Alveolar macrophages (AMs) play an essential role in ventilator‑induced lung injury (VILI).
Exosomes and their cargo, including microRNAs (miRNAs/miRs) serve as regulators of the …

Betanin Dose-Dependently Ameliorates Allergic Airway Inflammation by Attenuating Th2 Response and Upregulating cAMP–PKA–CREB Pathway in Asthmatic Mice

Q Li, Y Shen, X Guo, Y Xu, Y Mao, Y Wu… - Journal of Agricultural …, 2022 - ACS Publications
Allergic asthma is a refractory disease that affects hundreds of millions of people worldwide.
Betanin is a natural plant-derived nutrient and possesses health-promoting properties. The …