Emerging evidence suggests that liquid–liquid phase separation (LLPS) represents a vital
and ubiquitous phenomenon underlying the formation of membraneless organelles in …

Autophagy is a versatile degradation system for maintaining cellular homeostasis whereby
cytosolic materials are sequestered in a double-membrane autophagosome and …

Liquid–liquid phase separation (LLPS) is a novel principle for explaining the precise spatial
and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids …

Protein condensates are distinct structures assembled in living cells that concentrate
molecules via phase separation in a confined subcellular compartment. In the past decade …

Protein self-assembly is one of the formation mechanisms of biomolecular condensates.
However, most phase-separating systems (PS) demand multiple partners in biological …

Liquid–liquid phase separation (LLPS) of proteins into biomolecular condensates has
emerged as a fundamental principle underpinning cellular function and malfunction. Indeed …

Phase separation is a ubiquitous and emerging mechanism underlying intracellular
organization. Yet how distinct molecular compositions in phase-separated condensates are …

Biomolecular condensates play key roles in various biological processes. However, specific
condensation modulators are currently lacking. PROTAC is a new technology that can use …

Liquid-liquid phase separation (LLPS) has emerged as a mechanism that has been used to
explain the formation of known organelles (eg nucleoli, promyelocytic leukemia nuclear …

Liquid-liquid phase separation (LLPS) has received significant attention in recent biological
studies. It refers to a phenomenon that biomolecule exceeds the solubility, condensates and …