Duality of interactions between TGF-β and TNF-α during tumor formation

Z Liu, Y Zhang, L Zhang, T Zhou, Y Li, G Zhou… - Frontiers in …, 2022 - frontiersin.org
The tumor microenvironment is essential for the formation and development of tumors.
Cytokines in the microenvironment may affect the growth, metastasis and prognosis of …

A glimpse of the mechanisms related to renal fibrosis in diabetic nephropathy

LF Zeng, Y Xiao, L Sun - Renal Fibrosis: Mechanisms and Therapies, 2019 - Springer
Diabetic nephropathy (DN) is a common kidney disease in people with diabetes, which is
also a serious microvascular complication of diabetes and the main cause of end-stage …

[HTML][HTML] Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration

R Li, D Li, C Wu, L Ye, Y Wu, Y Yuan, S Yang, L Xie… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Autophagy in Schwann cells (SCs) is crucial for myelin debris
degradation and clearance following peripheral nerve injury (PNI). Nerve growth factor …

Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells

MG El Baassiri, L Dosh, H Haidar, A Gerges, S Baassiri… - Burns, 2023 - Elsevier
Burn wound healing is a very intricate and complex process that conventionally includes
three interrelated and overlapping stages of hemostasis/inflammation, proliferation and …

Cellular immune signal exchange from ischemic stroke to intestinal lesions through brain-gut axis

Z Yang, F Wei, B Zhang, Y Luo, X Xing… - Frontiers in …, 2022 - frontiersin.org
As a vital pivot for the human circulatory system, the brain-gut axis is now being considered
as an important channel for many of the small immune molecules' transductions, including …

The pleiotropic molecule NGF regulates the in vitro properties of fibroblasts, keratinocytes, and endothelial cells: implications for wound healing

N Gostynska, M Pannella, ML Rocco… - … of Physiology-Cell …, 2020 - journals.physiology.org
Nerve growth factor (NGF) is recognized as a pleiotropic molecule, exerting a variety of
biological effects on different cell types and pathophysiological conditions, and its role in …

Communications between peripheral and the brain-resident immune system in neuronal regeneration after stroke

F Liu, X Cheng, S Zhong, C Liu, J Jolkkonen… - Frontiers in …, 2020 - frontiersin.org
Cerebral ischemia may cause irreversible neural network damage and result in functional
deficits. Targeting neuronal repair after stroke potentiates the formation of new connections …

[HTML][HTML] IL-1β promotes stemness of tumor cells by activating Smad/ID1 signaling pathway

L Lu, P Wang, Y Zou, Z Zha, H Huang… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
Background: IL-1β is reported to be involved in cancer development and distant metastasis.
However, the underlying mechanism of IL-1β upon malignant behaviors remains largely …

Expression profiling and cell type classification analysis in periodontitis reveal dysregulation of multiple lncRNAs in plasma cells

D Wu, P Zhou, F Cao, Z Lin, D Liang, X Zhou - Frontiers in genetics, 2020 - frontiersin.org
Objective Periodontitis is a chronic inflammatory disease with a downregulated immune
response. The mechanisms of the immune response, especially regarding immune-related …

Growth factors expression and ultrastructural morphology after application of low-level laser and natural latex protein on a sciatic nerve crush-type injury

FJ Dias, VPS Fazan, DP Cury, SRY de Almeida… - PLoS …, 2019 - journals.plos.org
The effects of low-level laser therapy (LLLT) and natural latex protein (F1, Hevea
brasiliensis) were evaluated on crush-type injuries (15kg) to the sciatic nerve in the …