Epigenetic aberrations in major psychiatric diseases related to diet and gut microbiome alterations

S Nohesara, HM Abdolmaleky, S Thiagalingam - Genes, 2023 - mdpi.com
Nutrition and metabolism modify epigenetic signatures like histone acetylation and DNA
methylation. Histone acetylation and DNA methylation in the central nervous system (CNS) …

Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases

J Jang, SR Kim, JE Lee, S Lee, HJ Son… - International journal of …, 2023 - mdpi.com
Ketone bodies (KBs), such as acetoacetate and β-hydroxybutyrate, serve as crucial
alternative energy sources during glucose deficiency. KBs, generated through ketogenesis …

Exposure to methylmercury at juvenile stage worsens autism-like symptoms in adult BTBR T+ tf/J mice due to lack of nuclear factor erythroid 2-related factor 2 …

MM Algahtani, SF Ahmad, LA Alkharashi, NO Al-Harbi… - Toxics, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a multifaceted developmental condition that first appears
in infancy. The condition is characterized by recurrent patterns in behavior and impairments …

The early life exposome and autism risk: a role for the maternal microbiome?

CM Di Gesù, SA Buffington - Gut Microbes, 2024 - Taylor & Francis
Autism spectrum disorders (ASD) are highly heritable, heterogeneous neurodevelopmental
disorders characterized by clinical presentation of atypical social, communicative, and …

Therapeutic Potential of the Ketogenic Diet: A Metabolic Switch with Implications for Neurological Disorders, the Gut-Brain Axis, and Cardiovascular Diseases

S Shahpasand, SH Khatami, S Ehtiati… - The Journal of …, 2024 - Elsevier
Abstract The Ketogenic Diet (KD) is a dietary regimen that is low in carbohydrates, high in
fats, and contains adequate protein. It is designed to mimic the metabolic state of fasting …

Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the …

CR D'Adamo, JL Nelson, SN Miller… - Journal of Personalized …, 2024 - mdpi.com
The prevalence of autism has been increasing at an alarming rate. Even accounting for the
expansion of autism spectrum disorder diagnostic (ASD) criteria throughout the 1990's, there …

Mediterranean Ketogenic Diet Accounts for Reduced Pain Frequency and Intensity in Patients with Chronic Migraine: A pilot study

I Olivito, F Simona, A Tarsitano, M Pagliuso… - Clinical Nutrition, 2024 - Elsevier
Background An increasing amount of evidence suggests that migraine is a response to
cerebral energy deficiencies or oxidative stress levels that exceed antioxidant capacity …

Effects of Ketogenic Diet on Increased Ethanol Consumption Induced by Social Stress in Female Mice

L Torres-Rubio, MD Reguilón, S Mellado, M Pascual… - 2024 - preprints.org
Stress is a critical factor in the development of mental disorders such as addiction,
underscoring the importance of stress resilience strategies. While the ketogenic diet (KD) …

Reversal of Autism among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature

CR D'Adamo, JL Nelson, SN Miller, MR Hong… - 2024 - preprints.org
The prevalence of autism has been increasing at an alarming rate. Even accounting for the
expansion of autism spectrum disorder diagnostic (ASD) criteria throughout the 1990's, there …

Dietary beta-hydroxybutyrate is superior to a ketogenic diet to improve behavior and abnormal myelination in a mouse model of NMDA receptor deficiency

Y Yan, T Lipina, L Pepera, W Horsfall, A Salahpour… - 2024 - researchsquare.com
Background Dysfunction of N-methyl-D-aspartate receptors (NMDAR) is associated with
idiopathic autism and a syndromic form of autism called GRIN disorder. Ketogenic therapy is …