Although corticosteroids are the standard first-line therapy for pulmonary sarcoidosis, long-
term and high-dose use of these drugs are associated with increased risk of adverse events …

Idiopathic inflammatory myopathies (IIMs) are autoimmune disorders characterized by
symmetric proximal muscle weakness and chronic inflammation, with an increased risk of …

Introduction Long-term treatment of pulmonary sarcoidosis with glucocorticoids has been
associated with toxicity and other adverse events, highlighting the need for alternative …

Abstract Introduction About 20%–35% of multiple sclerosis (MS) patients fail to respond to
high‐dose corticosteroids during a relapse. Repository corticotropin injection (RCI, Acthar® …

We conducted a systematic review investigating the efficacy and tolerability of
adrenocorticotropic hormone (ACTH) and corticosteroids in children with epilepsies other …

Several inflammatory diseases are characterized by elevated T cell counts and high pro-
inflammatory cytokine levels. Inhibiting T cell activity may reduce tissue damage associated …

Purpose To investigate the response to Acthar Gel® in patients with moderate to severe
sarcoidosis uveitis. Methods This is a prospective open-label study that enrolled patients …

Acthar® Gel (repository corticotropin injection) is a naturally sourced complex mixture of
adrenocorticotropic hormone analogs and other pituitary peptides that is believed to have …

Introduction There is a substantial unmet need for effective therapies to treat patients with
refractory dry eye disease (DED). The goal of this open-label pilot study was to investigate …

Many peptide drugs such as insulin and glucagon-like peptide (GLP-1) analogues are
successfully administered subcutaneously (SC). Following SC injection, peptides may …