Fatty acid profile and genetic variants of proteins involved in fatty acid metabolism could be considered as disease predictor

R Chaaba, A Bouaziz, A Ben Amor, W Mnif… - Diagnostics, 2023 - mdpi.com
Circulating fatty acids (FA) have an endogenous or exogenous origin and are metabolized
under the effect of many enzymes. They play crucial roles in many mechanisms: cell …

Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid across twelve primary …

SK Venn-Watson, CN Butterworth - PloS one, 2022 - journals.plos.org
A growing body of evidence supports that pentadecanoic acid (C15: 0), an odd-chain
saturated fat found in butter, is an essential fatty acid that is necessary in the diet to support …

[HTML][HTML] Associations of serum n–3 and n–6 polyunsaturated fatty acids with prevalence and incidence of nonalcoholic fatty liver disease

TNK Mäkelä, TP Tuomainen, S Hantunen… - The American Journal of …, 2022 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver diseases
worldwide, and lifestyle and diet are significant factors in its development. Recent studies …

Antihypertensive effects of Nigella sativa supplementation: An updated systematic review and meta‐analysis of randomized controlled trials

Z Kavyani, V Musazadeh, E Safaei… - Phytotherapy …, 2023 - Wiley Online Library
Clinical studies have suggested that Nigella Sativa (N. sativa) supplementation may
effectively reduce blood pressure, but the findings are controversial. Therefore, this study …

17β-Estradiol protects female rats from bilateral oophorectomy-induced nonalcoholic fatty liver disease induced by improving linoleic acid metabolism alteration and …

Y Tian, Y Xie, X Hong, Z Guo, Q Yu - Heliyon, 2024 - cell.com
After surgical or natural menopause, women face a high risk of nonalcoholic fatty liver
disease (NAFLD), which can be diminished by hormone replacement therapy (HRT). The …

Associations of diet quality and food consumption with serum biomarkers for lipid and amino acid metabolism in Finnish children: the PANIC study

SE Laamanen, AM Eloranta, EA Haapala… - European Journal of …, 2024 - Springer
Purpose To investigate the associations of overall diet quality and dietary factors with serum
biomarkers for lipid and amino acid metabolism in a general population of children. Methods …

Metabolomic profiles of nonobese and obese women with gestational diabetes

H Sormunen-Harju, E Huvinen… - The Journal of …, 2023 - academic.oup.com
Context In non-pregnant population, nonobese individuals with obesity-related metabolome
have increased risk for type 2 diabetes and cardiovascular diseases. The risk of these …

Associations of specific dietary unsaturated fatty acids with risk of overweight/obesity: population-based cohort study

W Chen, Y Ao, X Lan, W Tong, X Liu, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background The role of specific unsaturated fatty acids (FAs) in the development of
overweight/obesity remains unclear in the general population. Here, we aimed to explore …

Excessive free fatty acid sensing in pituitary lactotrophs elicits steatotic liver disease by decreasing prolactin levels

X Ji, H Yin, T Gu, H Xu, D Fang, K Wang, H Sun, S Tian… - Cell Reports, 2024 - cell.com
The pituitary is the central endocrine gland with effects on metabolic dysfunction-associated
steatotic liver disease (MASLD). However, it is not clear whether the pituitary responds to …

Circulating fatty acids and risk of severe non-alcoholic fatty liver disease in the UK biobank: a prospective cohort of 116,223 individuals

P Zhuang, Y Ao, X Liu, H Ye, H Li, X Wan, Y Zhang… - Food & Function, 2024 - pubs.rsc.org
Fatty acid (FA) metabolism plays an important role in the development of nonalcoholic fatty
liver disease (NAFLD). However, data on the relation of circulating FAs with NAFLD risk are …