Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of
the gastrointestinal tract that arises due to complex interactions between host genetic risk …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease related to intestinal
dysbiosis. Luteolin has been reported to reduce inflammation. However, it remains unclear …

The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

The microbiome plays a key role in health and disease, and there has been considerable
interest in therapeutic targeting of the microbiome as well as mining this rich resource in …

Trillions of microbes have evolved with and continue to live on human beings. With the rapid
advances in tools and technology in recent years, new knowledge and insight in cross-talk …

The communities of bacteria that reside in the intestinal tract are in constant competition
within this dynamic and densely colonized environment. At homeostasis, the equilibrium that …

Vitamin D plays a pivotal role in intestinal homeostasis. Vitamin D can impact the function of
virtually every cell in the gut by binding to its intracellular receptor (VDR) and subsequently …

Environmental changes can induce diversity shifts within ecosystems that affect interactions
between species. Similarly, the development of kidney disease induces shifts within the …

Summary Type 1 diabetes (T1D) is an autoimmune disease, which is characterized by the
destruction of islet β cells in the pancreas triggered by genetic and environmental factors. In …

The current understanding of inflammatory bowel disease (IBD) pathogenesis implicates a
complex interaction between host genetics, host immunity, microbiome, and environmental …