Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer

W Zhu, N Miyata, MG Winter, A Arenales… - Journal of experimental …, 2019 - rupress.org
Chronic inflammation and gut microbiota dysbiosis, in particular the bloom of genotoxin-
producing E. coli strains, are risk factors for the development of colorectal cancer. Here, we …

Bifidobacterium longum Ameliorates Dextran Sulfate Sodium-Induced Colitis by Producing Conjugated Linoleic Acid, Protecting Intestinal Mechanical Barrier …

Y Chen, H Chen, J Ding, C Stanton… - Journal of Agricultural …, 2021 - ACS Publications
This study aimed to explore the effects and differences of conjugated linoleic acid (CLA)-
producing Bifidobacterium longum on the alleviation of dextran sulfate sodium (DSS) …

A designed whole-cell biosensor for live diagnosis of gut inflammation through nitrate sensing

SG Woo, SJ Moon, SK Kim, TH Kim, HS Lim… - Biosensors and …, 2020 - Elsevier
Microbes reprogrammed using advanced genetic circuits are envisaged as emerging living
diagnostics for a wide range of diseases and play key roles in regulating gut microbiota to …

Esterase-catalyzed siderophore hydrolysis activates an enterobactin–ciprofloxacin conjugate and confers targeted antibacterial activity

W Neumann, M Sassone-Corsi… - Journal of the …, 2018 - ACS Publications
Enteric Gram-negative bacteria, including Escherichia coli, biosynthesize and deploy the
triscatecholate siderophore enterobactin (Ent) in the vertebrate host to acquire iron, an …

[HTML][HTML] The progression of inorganic nanoparticles and natural products for inflammatory bowel disease

Q Li, L Lin, C Zhang, H Zhang, Y Ma, H Qian… - Journal of …, 2024 - Springer
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …

Oral delivery of bacteria: Basic principles and biomedical applications

S Li, W Jiang, C Zheng, D Shao, Y Liu, S Huang… - Journal of controlled …, 2020 - Elsevier
Bacterial therapy, which presents a smart platform for delivering and producing therapeutic
agents, as monotherapy or in combination with other therapeutic modes, has provided a …

Pharmacomicrobiomics: Influence of gut microbiota on drug and xenobiotic metabolism

IJ Dikeocha, AM Al‐Kabsi, M Miftahussurur… - The FASEB …, 2022 - Wiley Online Library
Gut microbiota is the most diverse and complex biological ecosystem, which is estimated to
consist of greater than 5 million distinct genes and 100 trillion cells which are in constant …

[HTML][HTML] Micronutrients impact the gut microbiota and blood glucose

NG Barra, FF Anhê, JF Cavallari… - Journal of …, 2021 - joe.bioscientifica.com
Micronutrients influence hormone action and host metabolism. Dietary minerals, trace
elements, and vitamins can alter blood glucose and cellular glucose metabolism, and …

Challenges in IBD research: environmental triggers

SM Ho, JD Lewis, EA Mayer… - Inflammatory bowel …, 2019 - academic.oup.com
Environmental triggers is part of five focus areas of the Challenges in IBD research
document, which also includes preclinical human IBD mechanisms, novel technologies …

[HTML][HTML] Sialic acid exacerbates gut dysbiosis-associated mastitis through the microbiota-gut-mammary axis by fueling gut microbiota disruption

C Zhao, X Hu, M Qiu, L Bao, K Wu, X Meng, Y Zhao… - Microbiome, 2023 - Springer
Background Mastitis is one of the most severe diseases in humans and animals, especially
on dairy farms. Mounting evidence indicates that gastrointestinal dysbiosis caused by …