Despite the recognition, nearly a century ago, that the human microbiome plays a clinically
relevant role in drug disposition, mechanistic insights, and translational applications are still …

The human gut microbiome is a complex microbial community that is strongly linked to both
host health and disease. However, the detailed molecular mechanisms underlying the …

The intestinal epithelium separates host tissue and gut-associated microbial communities.
During inflammation, the host releases reactive oxygen and nitrogen species as an …

Gastrointestinal (GI) tract, which possesses the largest surface area of mucosa in the body,
is easily suffered from inflammatory damages under the exposure of external stimulations …

Background & Aims Chronic colonic inflammation leads to dysplasia and cancer in patients
with inflammatory bowel disease. We have described the critical role of innate immune …

In this study, we employed a response surface methodology to optimize the
ultrasonic/microwave-assisted extraction (UMAE) conditions of Porphyra haitanensis …

Despite being one of the most world's widely used and mass-produced compounds,
bisphenol A (BPA) has a wide range of toxic effects. Bisphenol P (BPP), an alternative to …

Altered intestinal microbial composition (dysbiosis) and metabolic products activate
aggressive mucosal immune responses that mediate inflammatory bowel diseases (IBD) …

It has been claimed that Dendrobium officinale applied as a functional food in China for
centuries derived from the excellent anti-inflammatory activities. Herein, we aim to …

The effective delivery and colonization of probiotics are recommended for therapeutic
interventions during colitis, the efficacy of which is hampered by abnormally colonized …