Restless legs syndrome (RLS) is a common disorder. The population prevalence is 1.5% to
2.7% in a subgroup of patients having more severe RLS with symptoms occurring 2 or more …

Purposes Restless legs syndrome (RLS) is underdiagnosed and poorly understood by
clinicians and the general public alike; accordingly, a broad literature review with …

Background In 2003, following a workshop at the National Institutes of Health, the
International Restless Legs Syndrome Study Group (IRLSSG) developed updated …

Background Brain iron deficiency has been implicated in the pathophysiology of RLS, and
current RLS treatment guidelines recommend iron treatment when peripheral iron levels are …

A Task Force was established by the International Restless Legs Syndrome Study Group
(IRLSSG) to develop evidence-based and consensus-based recommendations for the long …

Restless Legs Syndrome (RLS) a common, under‐recognized disorder disrupts sleep and
diminishes quality of life. Despite a clear relation between low peripheral iron and increased …

Background Dopaminergic medications relieve symptoms of the restless legs syndrome
(RLS) but have the potential to cause iatrogenic worsening (augmentation) of RLS with long …

Background Specific diagnostic criteria for pediatric restless legs syndrome (RLS) were
published in 2003 following a workshop at the National Institutes of Health. Due to …

Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is common during pregnancy,
affecting approximately one in five pregnant women in Western countries. Many report …

Untreated sleep disorders may contribute to secondary causes of uncontrolled hypertension,
cardiovascular disease (CVD), and stroke. Restless legs syndrome, or Willis–Ekbom …