Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema

M Chilosi, A Carloni, A Rossi, V Poletti - Translational Research, 2013 - Elsevier
Different anatomic and physiological changes occur in the lung of aging people that can
affect pulmonary functions, and different pulmonary diseases, including deadly diseases …

[PDF][PDF] Depression's multiple comorbidities explained by (neuro) inflammatory and oxidative & nitrosative stress pathways

M Maes, M Kubera, E Obuchowiczwa… - Neuroendocrinol …, 2011 - researchgate.net
There is now evidence that depression, as characterized by melancholic symptoms, anxiety,
and fatigue and somatic (F&S) symptoms, is the clinical expression of peripheral cell …

[HTML][HTML] COPD surveillance—United States, 1999-2011

ES Ford, JB Croft, DM Mannino, AG Wheaton, X Zhang… - Chest, 2013 - Elsevier
This report updates surveillance results for COPD in the United States. For 1999 to 2011,
data from national data systems for adults aged≥ 25 years were analyzed. In 2011, 6.5% of …

Comorbidities and short-term prognosis in patients hospitalized for acute exacerbation of COPD: the EPOC en Servicios de medicina interna (ESMI) study

P Almagro, FJ Cabrera, J Diez, R Boixeda, MBA Ortiz… - Chest, 2012 - Elsevier
Background Comorbidities are frequent in patients hospitalized for COPD exacerbation, but
little is known about their relation with short-term mortality and hospital readmissions. Our …

Neutrophil-to-lymphocyte ratio in chronic obstructive pulmonary disease: a retrospective study

E Günay, S Sarınç Ulaşlı, O Akar, A Ahsen, S Günay… - Inflammation, 2014 - Springer
Chronic obstructive pulmonary disease (COPD) is a common chronic inflammatory disease
of the lung with a high mortality and morbidity rate. Some of the inflammatory markers such …

Nutrition as a modifiable factor in the onset and progression of pulmonary function impairment in COPD: A systematic review

LEJ van Iersel, RJ Beijers, HR Gosker… - Nutrition …, 2022 - academic.oup.com
Context Chronic obstructive lung disease (COPD) is a progressive lung disease
characterized by persistent airflow limitation. An increasing amount of evidence suggests an …

Inflammation in COPD: implications for management

S Sethi, DA Mahler, P Marcus, CA Owen… - The American journal of …, 2012 - Elsevier
Chronic obstructive pulmonary disease (COPD) is recognized by the Global Initiative for
Chronic Obstructive Lung Disease guidelines as an inflammatory disease state, and …

Renin–angiotensin system blockade: a novel therapeutic approach in chronic obstructive pulmonary disease

D Shrikrishna, R Astin, PR Kemp… - Clinical …, 2012 - portlandpress.com
ACE (angiotensin-converting enzyme) inhibitors and ARBs (angiotensin II receptor blockers)
are already widely used for the treatment and prevention of cardiovascular disease and their …

Melatonin reduces lung oxidative stress in patients with chronic obstructive pulmonary disease: a randomized, double‐blind, placebo‐controlled study

AG de Matos Cavalcante, PFC de Bruin… - Journal of pineal …, 2012 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD), a major cause of death and disability, is
attributed to an abnormal inflammatory response by the lungs to noxious substances …

Systemic LPS induces spinal inflammatory gene expression and impairs phrenic long-term facilitation following acute intermittent hypoxia

AG Huxtable, SMC Smith, S Vinit… - Journal of applied …, 2013 - journals.physiology.org
Although systemic inflammation occurs in most pathological conditions that challenge the
neural control of breathing, little is known concerning the impact of inflammation on …