Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives

N Vaou, E Stavropoulou, C Voidarou, C Tsigalou… - Microorganisms, 2021 - mdpi.com
The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery

U Anand, N Jacobo-Herrera, A Altemimi, N Lakhssassi - Metabolites, 2019 - mdpi.com
The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's
economy. Antibiotics, the bedrock, and wonder drug of the 20th century have played a …

[HTML][HTML] Antibacterial properties of polyphenols: characterization and QSAR (Quantitative structure–activity relationship) models

L Bouarab-Chibane, V Forquet, P Lantéri… - Frontiers in …, 2019 - frontiersin.org
Besides their established antioxidant activity, many phenolic compounds may exhibit
significant antibacterial activity. Here, the effect of a large dataset of 35 polyphenols on the …

[HTML][HTML] Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?

CL Gorlenko, HY Kiselev, EV Budanova… - Antibiotics, 2020 - mdpi.com
Infectious diseases that are caused by bacteria are an important cause of mortality and
morbidity in all regions of the world. Bacterial drug resistance has grown in the last decades …

Plant antimicrobial polyphenols as potential natural food preservatives

L Bouarab Chibane, P Degraeve… - Journal of the …, 2019 - Wiley Online Library
BACKGROUND The growing demand for natural food preservatives in the last decade has
promoted investigations on their application for preserving perishable foods. In this context …

The re-emergence of natural products for drug discovery in the genomics era

AL Harvey, RA Edrada-Ebel, RJ Quinn - Nature reviews drug discovery, 2015 - nature.com
Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …

[HTML][HTML] Development of botanicals to combat antibiotic resistance

PD Gupta, TJ Birdi - Journal of Ayurveda and integrative medicine, 2017 - Elsevier
The discovery of antibiotics in the previous century lead to reduction in mortality and
morbidity due to infectious diseases but their inappropriate and irrational use has resulted in …

Roles of plant volatiles in defence against microbial pathogens and microbial exploitation of volatiles

A Hammerbacher, TA Coutinho… - Plant, Cell & …, 2019 - Wiley Online Library
Plants emit a large variety of volatile organic compounds during infection by pathogenic
microbes, including terpenes, aromatics, nitrogen‐containing compounds, and fatty acid …

Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …