Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
Evaluating the atrial myopathy underlying atrial fibrillation: identifying the arrhythmogenic and thrombogenic substrate
JJ Goldberger, R Arora, D Green, P Greenland… - Circulation, 2015 - Am Heart Assoc
Atrial disease or myopathy forms the substrate for atrial fibrillation (AF) and underlies the
potential for atrial thrombus formation and subsequent stroke. Current diagnostic …
potential for atrial thrombus formation and subsequent stroke. Current diagnostic …
Lone atrial fibrillation: does it exist?
DG Wyse, IC Van Gelder, PT Ellinor, AS Go… - Journal of the American …, 2014 - jacc.org
The historical origin of the term “lone atrial fibrillation”(AF) predates by 60 years our current
understanding of the pathophysiology of AF, the multitude of known etiologies for AF, and …
understanding of the pathophysiology of AF, the multitude of known etiologies for AF, and …
Diastolic dysfunction and risk of atrial fibrillation: a mechanistic appraisal
MA Rosenberg, WJ Manning - Circulation, 2012 - Am Heart Assoc
Atrial fibrillation (AF) is the most common sustained arrhythmia, and its prevalence in the
population is increasing. 1 Diastolic dysfunction shares many common risk factors with AF …
population is increasing. 1 Diastolic dysfunction shares many common risk factors with AF …
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts
Idiopathic pulmonary fibrosis (IPF) is a lethal fibrotic lung disease in adults with limited
treatment options. Autophagy and the unfolded protein response (UPR), fundamental …
treatment options. Autophagy and the unfolded protein response (UPR), fundamental …
A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis
H Liang, C Zhang, T Ban, Y Liu, L Mei, X Piao… - The international journal …, 2012 - Elsevier
Cardiac fibrosis is characterized by aberrant proliferation of cardiac fibroblasts and
exaggerated deposition of extracellular matrix (ECM) in the myocardial interstitial, and …
exaggerated deposition of extracellular matrix (ECM) in the myocardial interstitial, and …
Atrial fibrosis as a dominant factor for the development of atrial fibrillation: facts and gaps
Atrial fibrillation (AF), the most commonly diagnosed arrhythmia, affects a notable
percentage of the population and constitutes a major risk factor for thromboembolic events …
percentage of the population and constitutes a major risk factor for thromboembolic events …
The relationship between atrial fibrillation and coronary artery disease: Understanding common denominators
M Mekhael, N Marrouche, AH El Hajjar… - Trends in cardiovascular …, 2022 - Elsevier
Atrial fibrillation (AF) and coronary artery disease (CAD) are highly prevalent cardiovascular
conditions. The coexistence of both diseases is common as they share similar risk factors …
conditions. The coexistence of both diseases is common as they share similar risk factors …
[HTML][HTML] MicroRNA-101a inhibits cardiac fibrosis induced by hypoxia via targeting TGFβRI on cardiac fibroblasts
X Zhao, K Wang, Y Liao, Q Zeng, Y Li, F Hu… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Hypoxia is a basic pathological challenge that is associated with
numerous cardiovascular disorders including aberrant cardiac remodeling. Transforming …
numerous cardiovascular disorders including aberrant cardiac remodeling. Transforming …
Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts
J Gu, X Liu, Q Wang, H Tan, M Guo, W Jiang… - Experimental cell …, 2012 - Elsevier
The activation of transforming growth factor-β1 (TGF-β1)/Smad signaling pathway and
increased expression of connective tissue growth factor (CTGF) induced by angiotensin II …
increased expression of connective tissue growth factor (CTGF) induced by angiotensin II …