Advances in understanding of biliary atresia pathogenesis and progression–a riddle wrapped in a mystery inside an enigma

M Davenport, R Kronfli, E Makin - Expert Review of …, 2023 - Taylor & Francis
Introduction Biliary atresia is a potentially fatal condition of the bile ducts–both intra-and
extrahepatic, for which we have no cure. Though principally a cholestatic condition, much of …

[HTML][HTML] Progress in biomarkers related to biliary atresia

F Kong, R Dong, G Chen, S Sun, Y Yang… - Journal of Clinical …, 2024 - ncbi.nlm.nih.gov
Biliary atresia (BA) is a congenital cholestatic disease that can seriously damage children's
liver function. It is one of the main reasons for liver transplantation in children. Early …

Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort

S Pandurangi, R Mourya, S Nalluri, L Fei, S Dong… - Hepatology, 2024 - journals.lww.com
Conclusions: Serum MMP-7 has high discriminative properties to differentiate BA from other
forms of neonatal cholestasis. MMP-7 cutoff values vary according to assay technology …

The magnetic resonance imaging and age-adjusted matrix metalloproteinase-7 assist the diagnosis of biliary atresia

JF Wu, SSF Peng, CS Tai, WH Lin, YM Jeng… - Journal of …, 2024 - Springer
Background We investigated the utilities of the liver-to-psoas apparent diffusion coefficient
ratios (LTPAR) yielded by diffusion-weighted magnetic resonance imaging (DWMRI) and the …

FIB-4 and APRI scores for progressive liver fibrosis diagnosis in children with biliary atresia

H Lyu, Y Ye, B Wang - Frontiers in Pediatrics, 2024 - frontiersin.org
Introduction Finding non-invasive methods to predict the degree of liver fibrosis is very
important in managing children with biliary atresia. Therefore, we explored the predictive …

Comparison for the diagnostic performance of early diagnostic methods for biliary atresia: a systematic review and network meta-analysis

Y Zhang, T Li, T Wang, Q Ji, J Zhan - Pediatric Surgery International, 2024 - Springer
Background Biliary atresia (BA), a progressive condition affecting canalicular-bile duct
function/anatomy, requires prompt surgical intervention for favorable outcomes. Therefore …

[HTML][HTML] Serum matrix metalloproteinase-7 for discriminating biliary atresia: a diagnostic accuracy and validation study

J Jiang, R Dong, M Du, G Chen… - Journal of …, 2024 - … -medicine.biomedcentral.com
Prompt and precise differential diagnosis of biliary atresia (BA) among cholestatic patients is
of great importance. Matrix metalloproteinase-7 (MMP-7) holds great promise as a …

Clinical Characteristics and Prognosis of Biliary Atresia with Low Serum Matrix Metalloproteinase-7 Levels

J Jiang, Y Yang, X Ren, C Xu, C Ye, J Zhou… - Journal of Pediatric …, 2024 - Elsevier
Purpose Serum matrix metalloproteinase-7 (MMP-7) levels can precisely differentiate biliary
atresia (BA) from non-BA cholestasis. However, serum MMP-7 levels of some BA patients …

Expedited Laparoscopic Cholangiogram and Liver Biopsy in the Workup of Biliary Atresia

K Lai, R Eldredge, DM Notrica, S Wadera… - Journal of pediatric …, 2023 - journals.lww.com
Purpose: Recent studies demonstrate the success of Kasai portoenterostomy for biliary
atresia (BA) is linearly related to infant age at time of Kasai. We sought to review the …

Serum matrix metalloproteinase-7 (MMP-7): As good as it gets?

M Davenport - Hepatology, 2024 - journals.lww.com
An expeditious diagnosis of biliary atresia (BA) allowing earlier specific surgical referral
would be a good thing, of that there should be no doubt. Delays in diagnosis, perhaps …