The Paf1 complex: a keystone of nuclear regulation operating at the interface of transcription and chromatin
The regulation of transcription by RNA polymerase II is closely intertwined with the
regulation of chromatin structure. A host of proteins required for the disassembly …
regulation of chromatin structure. A host of proteins required for the disassembly …
Nascent connections: R-loops and chromatin patterning
F Chédin - Trends in Genetics, 2016 - cell.com
RNA molecules, such as long noncoding RNAs (lncRNAs), have critical roles in regulating
gene expression, chromosome architecture, and the modification states of chromatin …
gene expression, chromosome architecture, and the modification states of chromatin …
[HTML][HTML] Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals
R-loops are three-stranded nucleic acid structures formed upon annealing of an RNA strand
to one strand of duplex DNA. We profiled R-loops using a high-resolution, strand-specific …
to one strand of duplex DNA. We profiled R-loops using a high-resolution, strand-specific …
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation
Transcription by RNA polymerase II (Pol II) is carried out by an elongation complex. We
previously reported an activated porcine Pol II elongation complex, EC*, encompassing the …
previously reported an activated porcine Pol II elongation complex, EC*, encompassing the …
The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states
BN Tomson, KM Arndt - Biochimica et Biophysica Acta (BBA)-Gene …, 2013 - Elsevier
The Paf1 complex was originally identified over fifteen years ago in budding yeast through
its physical association with RNA polymerase II. The Paf1 complex is now known to be …
its physical association with RNA polymerase II. The Paf1 complex is now known to be …
[HTML][HTML] Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
The conserved polymerase-associated factor 1 complex (Paf1C) plays multiple roles in
chromatin transcription and genomic regulation. Paf1C comprises the five subunits Paf1 …
chromatin transcription and genomic regulation. Paf1C comprises the five subunits Paf1 …
OsmiR530 acts downstream of OsPIL15 to regulate grain yield in rice
W Sun, XH Xu, Y Li, L Xie, Y He, W Li, X Lu… - New …, 2020 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small noncoding RNAs that play important roles in plant
growth and development as well as in stress responses. However, little is known about their …
growth and development as well as in stress responses. However, little is known about their …
Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin
AD Wier, MK Mayekar, A Héroux… - Proceedings of the …, 2013 - National Acad Sciences
Polymerase associated factor 1 complex (Paf1C) broadly influences gene expression by
regulating chromatin structure and the recruitment of RNA-processing factors during …
regulating chromatin structure and the recruitment of RNA-processing factors during …
ZMP recruits and excludes Pol IV–mediated DNA methylation in a site-specific manner
In plants, RNA-directed DNA methylation (RdDM) uses small interfering RNAs (siRNAs) to
target transposable elements (TEs) but usually avoids genes. RNA polymerase IV (Pol IV) …
target transposable elements (TEs) but usually avoids genes. RNA polymerase IV (Pol IV) …
[HTML][HTML] Integration of light and photoperiodic signaling in transcriptional nuclear foci
E Kaiserli, K Paldi, L O'Donnell, O Batalov… - Developmental cell, 2015 - cell.com
Light regulates major plant developmental transitions by orchestrating a series of nuclear
events. This study uncovers the molecular function of the natural variant, TZP (Tandem Zinc …
events. This study uncovers the molecular function of the natural variant, TZP (Tandem Zinc …