Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer

ACL Mortensen, H Berglund, M Hariri, E Papalanis… - Scientific Reports, 2023 - nature.com
Thyroid cancer is the most common endocrine malignancy, affecting nearly 600,000 new
patients worldwide. Treatment with the BRAF inhibitor sorafenib partially prolongs …

Utilizing CD44v6 and V600EBRAF-mutation for in vitro targeted combination therapy of thyroid carcinomas

ACL Mortensen, J Imgenberg-Kreuz, D Spiegelberg… - Heliyon, 2023 - cell.com
Aim The aim of this study was to assess the feasibility of targeted therapy of thyroid
carcinoma, first exploring potential targets BRAF, EGFR and CD44v6 in patient material …

Reminiscence therapy care program as a potential nursing intervention to relieve anxiety, depression, and quality of life in older papillary thyroid carcinoma patients: a …

L Chen, X Yang, X Ren, Y Lin - Frontiers in Psychology, 2022 - frontiersin.org
Objective Reminiscence therapy (RT) ameliorates psychological problems and quality of life
in cancer patients. However, no study reports its effect on older papillary thyroid carcinoma …

Diagnostic value of qualitative and quantitative parameters of contrast-enhanced ultrasound for differentiating differentiated thyroid carcinomas from benign nodules

J Fan, L Tao, W Zhan, W Li, L Kuang, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
Objective To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) of
qualitative and quantitative parameters for differentiating differentiated thyroid cancers from …

Machine learning algorithms for identifying contralateral central lymph node metastasis in unilateral cN0 papillary thyroid cancer

A Ren, J Zhu, Z Wu, J Ming, S Ruan, M Xu… - Frontiers in …, 2024 - frontiersin.org
Purpose The incidence of thyroid cancer is growing fast and surgery is the most significant
treatment of it. For patients with unilateral cN0 papillary thyroid cancer whether to dissect …

[HTML][HTML] The sensitivity of TIRADS scoring on ultrasonography in the management of thyroid nodules

K Anwar, AY Mohammad, S Khan - Pakistan Journal of Medical …, 2023 - ncbi.nlm.nih.gov
Objective: To determine the sensitivity of ACR-TIRADS scoring by comparing its results with
those obtained on biopsy of respective specimens. Method: This prospective study including …

Development and validation of nomograms for predicting survival in differentiated thyroid cancer patients with or without radioiodine therapy

B Ran, J Gong, J Shang, F Wei, H Xu - Frontiers in Oncology, 2023 - frontiersin.org
Objective This study aimed to establish and validate the nomograms for predicting overall
survival (OS) probabilities in differentiated thyroid cancer (DTC) patients who received and …

The value of the first postoperative diagnostic I-131 scan in patients with papillary thyroid carcinoma

B Ran, J Shang, Y Chen, M Zhou, H Li, W He… - Journal of Cancer …, 2024 - Springer
Objective To explore the feasibility of the postoperative diagnostic 131I whole-body planar
scans (Dx-WBS) in papillary thyroid cancer (PTC) patients, and to clarify its value for …

Analysis of delayed initial radioactive iodine therapy and clinical outcomes in papillary thyroid cancer: a two-center retrospective study

T He, M Li, Z Gao, X Li, H Zhong, C Ding… - Nuclear Medicine …, 2024 - journals.lww.com
Background It remains unclear whether the time interval between total thyroidectomy and
radioactive iodine (RAI) therapy influences clinical outcomes in papillary thyroid carcinoma …

Terrestrosin D inhibits invasion and induces apoptosis through inhibition of STAT3 in anaplastic thyroid carcinoma

H Zhang, D Sun, P Lei, J Cheng - Molecular & Cellular Toxicology, 2024 - Springer
Background The prognosis with current management approach of anaplastic thyroid
carcinoma (ATC) remains poor, and new effective treatments are greatly needed …