Hair loss affects millions of people at some time in their life, and safe and efficient treatments
for hair loss are a significant unmet medical need. We report that topical delivery of quercetin …

Genetic alterations are often acquired during prolonged propagation of pluripotent stem
cells (PSCs). This ruins the stem cell quality and hampers their full applications …

The human fallopian tube harbors the cell of origin for the majority of high-grade serous"
ovarian" cancers (HGSCs), but its cellular composition, particularly the epithelial component …

As part of the Human Cell Atlas Initiative, our goal is to generate single-cell transcriptomics
(single-cell RNA sequencing [scRNA-seq], 86,708 cells) and regulatory (single-cell assay on …

The mechanism underlying the role of oxidative stress and advanced oxidation protein
products (AOPPs) in the aetiology of premature ovarian insufficiency (POI) is poorly …

Rationale: Accumulated evidence indicates that environmental plasticizers are a threat to
human and animal fertility. Di (2-ethylhexyl) phthalate (DEHP), a plasticizer to which humans …

Oocyte maturation disorder and decreased quality are the main causes of infertility in
women, and granulosa cells (GCs) provide the only microenvironment for oocyte maturation …

Primary ovarian insufficiency (POI) is an ovarian dysfunction that affects more than 1% of
women and is characterized by hormone imbalances that afflict women before the age of 40 …

Metformin (MET) and nicotinamide riboside (NR) have both been reported to exert
geroprotective effects in multiple species. However, the mechanism by which MET and NR …

The hippocampus plays a crucial role in learning and memory, and its progressive
deterioration with age is functionally linked to a variety of human neurodegenerative …