Context This overview presents the updated European Association of Urology (EAU)
guidelines for muscle-invasive and metastatic bladder cancer (MMIBC). Objective To …

Urological cancers are among the most common malignancies around the world. In
particular, bladder cancer severely threatens human health due to its aggressive and …

Background Standard treatment for high-risk non-muscle-invasive bladder cancer is
transurethral resection of bladder tumour followed by intravesical BCG immunotherapy …

PURPOSE The optimal perioperative chemotherapy regimen for patients with nonmetastatic
muscle-invasive bladder cancer is not defined. PATIENTS AND METHODS Between …

Context Management of bladder cancer (BC) is primarily driven by stage, grade, and
biological potential. Knowledge of each is derived using clinical, histopathological, and …

Bladder cancer is a highly prevalent disease and is associated with substantial morbidity,
mortality and cost. Environmental or occupational exposures to carcinogens, especially …

Background Perioperative chemotherapy (neoadjuvant or adjuvant) has been developed to
increase overall survival for nonmetastatic muscle-invasive bladder cancer (MIBC) …

Background Patients with predominant variant histology (VH) of bladder tumors, defined as
involving> 50% of the tumor specimens, are typically excluded from clinical trials, and for …

Background Novel second-line treatments are needed for patients with advanced urothelial
cancer (UC). Interim analysis of the phase III KEYNOTE-045 study showed a superior overall …

Increasing evidences suggest that circular RNA s (circ RNA s) exert crucial functions in
regulating gene expression. In this study, we perform RNA‐seq and identify 6,154 distinct …