Malaria remains a important global disease with more than 200 million cases and 600 000
deaths each year. Malaria-associated acute kidney injury (MAKI) may occur in up to 40% of …

Introduction Cerebral malaria is one of the most severe manifestations of malaria and is a
leading cause of acquired neurodisability in African children. Recent studies suggest acute …

Febrile symptoms in children are a leading cause of health-care seeking behaviour
worldwide. The majority of febrile illnesses are uncomplicated and self-limited, without the …

Background Children with sickle cell anemia (SCA) are at increased risk of acute kidney
injury (AKI) that may lead to death or chronic kidney disease. This study evaluated AKI …

Autoantibodies are frequently reported in patients with malaria, but whether they contribute
to protection or to pathology is an issue of debate. A large body of evidence indicates that …

Plasmodium falciparum malaria is classified as either uncomplicated or severe, determining
clinical management and providing a framework for understanding pathogenesis. Severe …

Background Understanding the relationship between malaria infection risk and disease
outcomes represents a fundamental component of morbidity and mortality burden …

Abstract Purpose of Review We highlight the unique facets of paediatric nephrology in Africa
in terms of the spectrum of kidney diseases, available diagnostic and treatment modalities …

Background Malaria is an important cause of mortality in African children. Identification of
biomarkers to identify children at risk of mortality has the potential to improve outcomes …

Background Acute kidney injury (AKI) is highly associated with mortality risk in children
worldwide. Trauma can lead to AKI and is a leading cause of pediatric death in Africa …