Digital image analysis and machine learning-assisted prediction of neoadjuvant chemotherapy response in triple-negative breast cancer

TB Fisher, G Saini, TS Rekha, J Krishnamurthy… - Breast Cancer …, 2024 - Springer
Background Pathological complete response (pCR) is associated with favorable prognosis
in patients with triple-negative breast cancer (TNBC). However, only 30–40% of TNBC …

Association of quantitative analysis of intratumoral reduced E-cadherin expression with lymph node metastasis and prognosis in patients with breast cancer

X Meng, M Morita, S Kuba, H Hayashi, R Otsubo… - Scientific Reports, 2023 - nature.com
Loss of E-cadherin expression is a poor prognostic factor in patients with breast cancer.
Breast cancer cells co-cultured with adipocytes reportedly promote E-cadherin attenuation …

Clinical significance of peritumoral adipose tissue PET/CT imaging features for predicting axillary lymph node metastasis in patients with breast cancer

JW Lee, SY Kim, SW Han, JE Lee, SH Hong… - Journal of Personalized …, 2021 - mdpi.com
We investigated whether textural parameters of peritumoral breast adipose tissue (AT)
based on F-18 fluorodeoxyglucose (FDG) PET/CT could predict axillary lymph node …

[HTML][HTML] Age and obesity-driven changes in the extracellular matrix of the primary tumor and metastatic site influence tumor invasion and metastatic outgrowth

SJ Conner, JR Guarin, HB Borges, KJ Salhany Jr… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Younger age and obesity increase the incidence and metastasis of triple-negative breast
cancer (TNBC), an aggressive subtype of breast cancer. The extracellular matrix (ECM) …

Monitoring adipose tissue invasion in breast cancer by multiphoton microscopy

Y Feng, J Miao, S Zhang, L Zheng… - Optics in Health …, 2022 - spiedigitallibrary.org
Adipocytes are considered to be a critical cell type in the tumor microenvironment of breast
cancer. Many studies have confirmed that adipocytes are not only found adjacent to cancer …

[引用][C] Investigation of epigenetic influences on DNA methylation in Triple Negative Breast Cancer

K Northwood - 2022 - espace.library.uq.edu.au
Breast cancer (BC) has long been recognised as a heterogeneous disease entity, with
multiple subtypes. One outstanding clinical problem relates to improving clinical decision …