Abstract FBXW7 (F-Box and WD Repeat Domain Containing 7)(also referred to as FBW7 or
hCDC4) is a component of the Skp1-Cdc53/Cullin-F-box-protein complex (SCF/β-TrCP). As …

Acute myeloid leukemia (AML) is the most common acute leukemia in adults. The
pathophysiology of this disease is just beginning to be understood at the cellular and …

Background When a new pathogen, such as severe acute respiratory syndrome coronavirus
2, appears all novel information can aid in the process of monitoring and in the diagnosis of …

Hematological malignancies (HM) are a collection of malignant transformations originating
from cells in the primary or secondary lymphoid organs. Leukemia, lymphoma, and multiple …

Exosomes, known as a type of extracellular vesicles (EVs), are lipid particles comprising
heterogeneous contents such as nucleic acids, proteins, and DNA. These bi-layered …

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide, with
890,000 new cases and 450,000 deaths in 2018, and although the survival statistics for …

Leukemia is known as a progressive malignant disease, which destroys the blood‐forming
organs and results in adverse effects on the proliferation and development of leukocytes and …

The development of better diagnostic and prognostic non-invasive biomarkers holds an
enormous potential to improve the ability to diagnose and individualize treatment of a great …

Early-stage detection of leukemia is a critical determinant for successful treatment of the
disease and can increase the survival rate of leukemia patients. The factors limiting the …

Dysregulated apoptosis and proliferation are fundamental properties of cancer, and
microRNAs (miRNA) are critical regulators of these processes. Loss of miR-15a/16-1 at …