Within the last years, the use of stem cells (embryonic, induced pluripotent stem cells, or
hematopoietic stem cells), Progenitor cells (eg, endothelial progenitor cells), and most …

The shortage of donor organs is a major global concern. Organ failure requires the
transplantation of functional organs. Donor's organs are preserved for variable periods of …

The administration of certain progenitor cells is protective in experimental acute kidney
injury (AKI), and mechanisms may involve the release of paracrine factors. Endothelial …

Cardiovascular disease is a major health problem in industrialized and developing countries
and is the leading cause of death and disability. Myocardial ischemia/reperfusion (I/R) …

Apoptosis and fibrosis play a vital role in myocardial infarction (MI) induced tissue injury.
Although microRNAs have been the focus of many studies on cardiac apoptosis and fibrosis …

The levels of fibroblast growth factor 23 (FGF23) rapidly increases after acute kidney injury
(AKI). However, the role of FGF23 in AKI is still unclear. Here, we observe that pretreatment …

Aloperine is a quinolizidine alkaloid extracted from the leaves of Sophora plants. It has been
recognized with the potential to treat inflammatory and allergic diseases as well as tumors …

Stroke remains a major unmet clinical need that warrants novel therapies. Following an
ischemic insult, the cerebral vasculature secretes inflammatory molecules, creating the …

In addition to its important transport functions, the skeletal system is involved in complex
biological activities for the regulation of blood vessels. Endothelial progenitor cells (EPCs) …

Background Renal ischemia–reperfusion (I/R) injury is a major cause of acute kidney injury
(AKI), which is associated with high morbidity and mortality. AKI is a serious and costly …