Management of hypertension and cardiovascular risk

NK Hollenberg - The American journal of medicine, 1991 - Elsevier
Blood pressure reduction in hypertensive patients is a surrogate for the real therapeutic goal
of reducing the risks consequent to hypertension. This surrogate is convenient but its use …

Effects of acute and chronic cilazapril treatment in spontaneously hypertensive rats.

W Fischli, F Hefti, JP Clozel - British Journal of Clinical …, 1989 - Wiley Online Library
1. The effects of acute and chronic treatment with cilazapril, a new ACE inhibitor, on
peripheral vasculature and renal excretory function were assessed in spontaneously …

Sympathetic modulation of renal blood flow by rilmenidine and captopril: central vs. peripheral effects

BJA Janssen, EV Lukoshkova… - American Journal of …, 2002 - journals.physiology.org
Renal blood flow (RBF) is modulated by renal sympathetic nerve activity (RSNA). However,
agents that are supposed to reduce sympathetic tone, such as rilmenidine and captopril …

Histopathological investigation on salt-loaded stroke-prone spontaneously hypertensive rats, whose biochemical parameters of renal dysfunction were ameliorated by …

T Fujiwara, H Yuasa, N Ogiku, Y Kawai - The Japanese Journal of …, 1994 - jstage.jst.go.jp
Our previous studies showed that imidapril prevented the occurrence of cerebral stroke and
ameliorated biochemical parameter changes of renal dysfunction at a dose that did not …

Left ventricular hypertrophy: a pathophysiological and molecular biological perspective

D Susic, ED Frohlich - Hypertension Research, 1993 - jstage.jst.go.jp
This review provides a brief summary of molecular and pathophysiological events involved
in the development and reversal of hypertensive left ventricular hypertrophy(LVH). Data …

Comparative pharmacokinetic and clinical profiles of angiotensin-converting enzyme inhibitors and calcium antagonists in systemic hypertension

WH Frishman - The American journal of cardiology, 1992 - Elsevier
Angtotensin-converting enzyme (ACE) inhibitors and calcium antagonists are important
classes of antihypertensive agents. Within their respective classes, ACE inhibitors and …

Regression of left ventricular hypertrophy in hypertensive elderly patients with carvedilol

M Verza, S Ammendola, A Cambardella, G Scoti… - Archives of Gerontology …, 1996 - Elsevier
In hypertensive patients, the development of left ventricular hypertrophy seems to increase
the risk of cardiovascular death although some antihypertensive agents have been …

Reversal of target-organ involvement in systemic hypertension: a pharmacologic experience

ED Frohlich - The American Journal of Cardiology, 1987 - Elsevier
Systemic hypertension is a disease manifested by a persistently elevated arterial pressure
produced by an increased total peripheral resistance, which is more or less uniformly …

Cardiac involvement in hypertension

DJ DiPette, ED Frohlich - The American Journal of Cardiology, 1988 - Elsevier
Despite improved patient detection and pharmacologic therapy, the effect of treatment of
hypertension on mortality from coronary artery-related events remains unresolved. Left …

Doppler waveforms in the renal arteries of normal children

DM Friedman, RG Schacht - Journal of clinical ultrasound, 1991 - Wiley Online Library
Blood velocity waveforms in peripheral arteries vary such that decreasing vascular
resistance results in a relative increase in diastolic velocity at steady state. We measured …