[HTML][HTML] Research advances in peptide‒drug conjugates

L Gong, H Zhao, Y Liu, H Wu, C Liu, S Chang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Peptide‒drug conjugates (PDCs) are drug delivery systems consisting of a drug covalently
coupled to a multifunctional peptide via a cleavable linker. As an emerging prodrug strategy …

DNA‐based nanoarchitectures as eminent vehicles for smart drug delivery systems

M Komiyama, N Shigi, K Ariga - Advanced Functional Materials, 2022 - Wiley Online Library
In order to cure diseases efficiently with minimal side effects in sophisticated medicine,
eminent drugs must be selectively delivered to diseased parts and allow to work only there …

[HTML][HTML] GSH-responsive SN38 dimer-loaded shape-transformable nanoparticles with iRGD for enhancing chemo-photodynamic therapy

C Lin, F Tong, R Liu, R Xie, T Lei, Y Chen… - … Pharmaceutica Sinica B, 2020 - Elsevier
Accurate tumor targeting, deep penetration and superb retention are still the main pursuit of
developing excellent nanomedicine. To achieve these requirements, a stepwise stimuli …

Synthesis and Characterization of Lyophilized Chitosan‐Based Hydrogels Cross‐Linked with Benzaldehyde for Controlled Drug Release

F Damiri, Y Bachra, C Bounacir, A Laaraibi… - Journal of …, 2020 - Wiley Online Library
In this study, chitosan‐based hydrogels were produced by incorporating three drugs with a
different solubility into a polymer matrix. The lyophilized chitosan salt was prepared using an …

Degradation behavior of polymers used as coating materials for drug delivery—A basic review

AI Visan, G Popescu-Pelin, G Socol - Polymers, 2021 - mdpi.com
The purpose of the work was to emphasize the main differences and similarities in the
degradation mechanisms in the case of polymeric coatings compared with the bulk ones …

Engineering Escherichia coli Nissle 1917 as a microbial chassis for therapeutic and industrial applications

M Yu, S Hu, B Tang, H Yang, D Sun - Biotechnology Advances, 2023 - Elsevier
Genetically engineered microbes, especially Escherichia coli, have been widely used in the
biosynthesis of proteins and metabolites for medical and industrial applications. As a …

Self-assembling nanocarriers from engineered proteins: Design, functionalization, and application for drug delivery

Y Li, JA Champion - Advanced Drug Delivery Reviews, 2022 - Elsevier
Self-assembling proteins are valuable building blocks for constructing drug nanocarriers
due to their self-assembly behavior, monodispersity, biocompatibility, and biodegradability …

Electrospinning technologies for the delivery of biopharmaceuticals: Current status and future trends

S Lian, D Lamprou, M Zhao - International Journal of Pharmaceutics, 2023 - Elsevier
This review provides an in-depth exploration of electrospinning techniques employed to
produce micro-or nanofibres of biopharmaceuticals using polymeric solutions or melts with …

Novel drug delivery strategies for antidepressant active ingredients from natural medicinal plants: the state of the art

S Yuan, T Ma, YN Zhang, N Wang, Z Baloch… - Journal of …, 2023 - Springer
Depression is a severe mental disorder among public health issues. Researchers in the field
of mental health and clinical psychiatrists have long been faced with difficulties in slow …

[HTML][HTML] Nano drug delivery in intracellular bacterial infection treatments

SM Hosseini, M Taheri, F Nouri, A Farmani… - Biomedicine & …, 2022 - Elsevier
The present work aimed to review the potential mechanisms used by macrophages to kill
intracellular bacteria, their entrance to the cell, and mechanisms of escape of cellular …