A review of current advancements for wound healing: Biomaterial applications and medical devices

X Deng, M Gould, MA Ali - Journal of Biomedical Materials …, 2022 - Wiley Online Library
Wound healing is a complex process that is critical in restoring the skin's barrier function.
This process can be interrupted by numerous diseases resulting in chronic wounds that …

Chronic wounds: Current status, available strategies and emerging therapeutic solutions

K Las Heras, M Igartua, E Santos-Vizcaino… - Journal of controlled …, 2020 - Elsevier
In the past decades, adequate and well-planned management of chronic wounds has
reached an elevated importance to improve human's quality of life and extend life …

Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies

P Rousselle, F Braye, G Dayan - Advanced Drug Delivery Reviews, 2019 - Elsevier
Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …

Improving chronic diabetic wound healing through an injectable and self-healing hydrogel with platelet-rich plasma release

Z Qian, H Wang, Y Bai, Y Wang, L Tao… - … applied materials & …, 2020 - ACS Publications
Diabetic skin ulcer is one of the severe complications of diabetes mellitus, which has a high
incidence and may cause death or disability. Platelet-rich plasma (PRP) is widely used in …

Skin tissue regeneration for burn injury

A Shpichka, D Butnaru, EA Bezrukov… - Stem cell research & …, 2019 - Springer
The skin is the largest organ of the body, which meets the environment most directly. Thus,
the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a …

Adipose mesenchymal stem cell‐derived exosomes promote cell proliferation, migration, and inhibit cell apoptosis via Wnt/β‐catenin signaling in cutaneous wound …

T Ma, B Fu, X Yang, Y Xiao… - Journal of Cellular …, 2019 - Wiley Online Library
Cutaneous wounds, a type of soft tissue injury, are difficult to heal in aging. Differentiation,
migration, proliferation, and apoptosis of skin cells are identified as key factors during wound …

Mesenchymal stem cells in fibrotic diseases—the two sides of the same coin

L Qin, N Liu, C Bao, D Yang, G Ma, W Yi… - Acta Pharmacologica …, 2023 - nature.com
Fibrosis is caused by extensive deposition of extracellular matrix (ECM) components, which
play a crucial role in injury repair. Fibrosis attributes to~ 45% of all deaths worldwide. The …

Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway

N Ebrahim, AA Dessouky, O Mostafa… - Stem cell research & …, 2021 - Springer
Background Diabetic foot ulceration is a serious chronic complication of diabetes mellitus
characterized by high disability, mortality, and morbidity. Platelet-rich plasma (PRP) has …

ADSC-Exos containing MALAT1 promotes wound healing by targeting miR-124 through activating Wnt/β-catenin pathway

L He, C Zhu, J Jia, XY Hao, XY Yu, XY Liu… - Bioscience …, 2020 - portlandpress.com
Cutaneous wound is a soft tissue injury that is difficult to heal during aging. It has been
demonstrated that adipose-derived stem cells (ADSCs) and its secreted exosomes exert …

MFG-E8 accelerates wound healing in diabetes by regulating “NLRP3 inflammasome-neutrophil extracellular traps” axis

W Huang, J Jiao, J Liu, M Huang, Y Hu, W Ran… - Cell death …, 2020 - nature.com
Sustained activation of NLRP3 inflammasome and release of neutrophil extracellular traps
(NETs) impair wound healing of diabetic foot ulcers (DFUs). Our previous study reported that …