The past decade of progress in neurobiology has uncovered important organizational
principles for network preconfiguration and neuronal selection that suggest a generative …

For adaptive real-time behavior in real-world contexts, the brain needs to allow past
information over multiple timescales to influence current processing for making choices that …

Little is understood about how engrams, sparse groups of neurons that store memories, are
formed endogenously. Here, we combined calcium imaging, activity tagging, and …

Many theories of offline memory consolidation posit that the pattern of neurons activated
during a salient sensory experience will be faithfully reactivated, thereby stabilizing the …

Neuronal firing sequences are thought to be the basic building blocks of neural coding and
information broadcasting within the brain. However, when sequences emerge during …

The brain is capable of solving complex problems simply and efficiently, far surpassing
modern computers. In this regard, neuromorphic engineering focuses on mimicking the …

During both sleep and awake immobility, hippocampal place cells reactivate time-
compressed versions of sequences representing recently experienced trajectories in a …

Episodic memory function is predicated upon the precise coordination between the
hippocampus and widespread cortical regions. However, our understanding of the neural …

Every day, we experience new daily episodes and store new memories. Although memories
are stored in corresponding engram cells, how different sets of engram cells are selected for …

Animals learn from past experience to guide future behavior and improve survival. This
ability relies in part on specific episodic memories of past events encoded by neuronal …