[HTML][HTML] Eosinophil-mucus interplay in severe asthma: Implications for treatment with biologicals

CV Garrido, M Mukherjee, S Svenningsen… - Allergology International, 2024 - Elsevier
Airway mucus is a hydrogel with unique biophysical properties due to its primary water
composition and a small proportion of large anionic glycoproteins or mucins. The …

Tezepelumab and mucus plugs in patients with moderate-to-severe asthma

LH Nordenmark, Å Hellqvist, C Emson, S Diver… - NEJM …, 2023 - evidence.nejm.org
Background Mucus plugs in asthmatic airways are associated with airway obstruction and
the activity of inflammatory cytokines, specifically interleukin (IL)-5 and IL-13, and they may …

Automated detection of broncho-arterial pairs using CT scans employing different approaches to classify lung diseases

S Azam, AKMRH Rafid, S Montaha, A Karim… - Biomedicines, 2023 - mdpi.com
Current research indicates that for the identification of lung disorders, comprising
pneumonia and COVID-19, structural distortions of bronchi and arteries (BA) should be …

Symptomatic smokers without COPD have physiological changes heralding the development of COPD

E Bazzan, U Semenzato, G Turato… - ERJ Open …, 2022 - Eur Respiratory Soc
Background COPD is a major health problem, mainly due to cigarette smoking. Most studies
in COPD are dedicated to fully developed COPD in older subjects, even though …

Silent airway mucus plugs in COPD and clinical implications

SK Mettler, HP Nath, S Grumley, JL Orejas, WR Dolliver… - Chest, 2023 - Elsevier
Background Airway mucus plugs are frequently identified on CT scans of patients with
COPD with a smoking history without mucus-related symptoms (ie, cough, phlegm [silent …

[HTML][HTML] Re-evaluation for systematic reviews of traditional Chinese medicine in the treatment of chronic bronchitis

Y Deng, L Xi, S Han, T Liang, H Huang, Y Fan… - Medicine, 2023 - journals.lww.com
Background: Chronic bronchitis (CB) is a common clinical chronic respiratory disease, which
has a high incidence in the middle aged and elderly population. With the development of the …

[HTML][HTML] Airway Mucus Plugs in Community-Living Adults: A Study Protocol

M Abdalla, R Elalami, MH Cho, GT O'Connor, M Rice… - medRxiv, 2024 - ncbi.nlm.nih.gov
Introduction: Mucus pathology plays a critical role in airway diseases like chronic bronchitis
(CB) and chronic obstructive pulmonary disease (COPD). Up to 32% of community-living …

[PDF][PDF] 烟雾刺激法诱导呼吸系统疾病动物模型的研究及应用进展

邓亚胜, 林江, 黄慧, 梁天薇, 荣娜, 郑艺清… - 中国比较医学 …, 2023 - zgbjyx.cnjournals.com
环境空气污染对人类呼吸系统造成了严重的损害, 增加了罹患呼吸系统疾病的风险.
烟雾刺激法是临床动物实验中常用于制备呼吸系统疾病动物模型的造模方法 …

[PDF][PDF] Automated Detection of Broncho-Arterial Pairs Using CT Scans Employing Different Approaches to Classify Lung Diseases. Biomedicines 2023, 11, 133

S Azam, ARH Rafid, S Montaha, A Karim, M Jonkman… - 2023 - researchgate.net
Current research indicates that for the identification of lung disorders, comprising
pneumonia and COVID-19, structural distortions of bronchi and arteries (BA) should be …

Hypoxic conditions promote a proliferative, poorly differentiated, and pro-secretory phenotype in COPD lung tissue progenitor cells in vitro

TP Dale, MD Santer, M Haris, W Zuo, NR Forsyth - bioRxiv, 2022 - biorxiv.org
Chronic obstructive pulmonary disease patients experience variable symptoms dependent
on the presence of an emphysematous versus a chronic bronchitis phenotype. Both …