[HTML][HTML] From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery
KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
[HTML][HTML] COVID-19 and antiphospholipid antibodies: time for a reality check?
Antiphospholipid antibodies (aPL) comprise a panel of autoantibodies that reflect a potential
prothrombotic risk in several autoimmune conditions, most notably antiphospholipid …
prothrombotic risk in several autoimmune conditions, most notably antiphospholipid …
How to optimize activated partial thromboplastin time (APTT) testing: solutions to establishing and verifying normal reference intervals and assessing APTT reagents …
EJ Favaloro, G Kershaw… - … in thrombosis and …, 2019 - thieme-connect.com
The activated partial thromboplastin time (APTT) assay is a very common coagulation test,
used for several reasons. The test is conventionally used for assessing the contact factor …
used for several reasons. The test is conventionally used for assessing the contact factor …
Antiphospholipid antibodies in COVID-19-associated pneumonia patients in intensive care unit
Abstract Objectives Antiphospholipid antibodies (APAs) increase the risk of excessive blood
clotting, but their role in COVID‐19 remains unclear. We aimed to investigate the presence …
clotting, but their role in COVID‐19 remains unclear. We aimed to investigate the presence …
[HTML][HTML] Molecular mechanisms of “antiphospholipid antibodies” and their paradoxical role in the pathogenesis of “seronegative APS”
R Misasi, A Longo, S Recalchi, D Caissutti… - International Journal of …, 2020 - mdpi.com
Antiphospholipid Syndrome (APS) is an autoimmune disease characterized by arterial
and/or venous thrombosis and/or pregnancy morbidity, associated with circulating …
and/or venous thrombosis and/or pregnancy morbidity, associated with circulating …
Cell-bound complement activation products in SLE
R Ramsey-Goldman, J Li, T Dervieux… - Lupus science & …, 2017 - lupus.bmj.com
Diagnosis of SLE is based on clinical manifestations and laboratory findings. Timely
diagnosis and treatment are important to control disease activity and prevent organ damage …
diagnosis and treatment are important to control disease activity and prevent organ damage …
Genetic testing for thrombophilia-related genes: observations of testing patterns for factor V Leiden (G1691A) and prothrombin gene “Mutation”(G20210A)
EJ Favaloro - Seminars in thrombosis and hemostasis, 2019 - thieme-connect.com
Thrombophilia is a generic term that defines an increased propensity toward thrombosis and
associated morbidity. Factor V Leiden (FVL; G1691A) and the prothrombin gene mutation …
associated morbidity. Factor V Leiden (FVL; G1691A) and the prothrombin gene mutation …
[HTML][HTML] Bioactive molecules derived from snake venoms with therapeutic potential for the treatment of thrombo-cardiovascular disorders associated with COVID-19
F Chérifi, F Laraba-Djebari - The protein journal, 2021 - Springer
As expected, several new variants of Severe Acute Respiratory Syndrome-CoronaVirus-2
(SARS-CoV-2) emerged and have been detected around the world throughout this …
(SARS-CoV-2) emerged and have been detected around the world throughout this …
Antiphospholipid syndrome: Diagnosis and management in the obstetric patient
E Arslan, DW Branch - Best practice & research Clinical obstetrics & …, 2020 - Elsevier
Antiphospholipid syndrome (APS) is a rare condition clinically characterized by thrombotic
events or pregnancy complications and confirmed by one or more repeatedly positive …
events or pregnancy complications and confirmed by one or more repeatedly positive …
[HTML][HTML] “New” antigenic targets and methodological approaches for refining laboratory diagnosis of antiphospholipid syndrome
R Misasi, A Capozzi, A Longo, S Recalchi… - Journal of immunology …, 2015 - hindawi.com
Antiphospholipid antibodies (aPLs) are a heterogeneous group of antibodies directed
against phospholipids or protein/phospholipid complexes. Currently, aPLs are assessed …
against phospholipids or protein/phospholipid complexes. Currently, aPLs are assessed …