Dual Antiplatelet Therapy for the Acute Management and Long-term Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack, An Updated Review

BPL Chan, LYH Wong, BYQ Tan, LLL Yeo… - Journal of …, 2024 - mdpi.com
To improve the efficacy over antiplatelet monotherapy, dual antiplatelet therapy (DAPT) has
been increasingly adopted in the management of non-cardioembolic stroke. For minor …

[HTML][HTML] Developing targeted antioxidant nanomedicines for ischemic penumbra: Novel strategies in treating brain ischemia-reperfusion injury

Z Hou, JS Brenner - Redox Biology, 2024 - Elsevier
During cerebral ischemia-reperfusion conditions, the excessive reactive oxygen species in
the ischemic penumbra region, resulting in neuronal oxidative stress, constitute the main …

[PDF][PDF] Extending Dual Antiplatelet Therapy for TIA or Stroke

AS Kim - The New England Journal of Medicine, 2023 - bookcafe.yuntsg.com
Although stroke is typically understood to be a medical emergency, the same pertains when
cerebral ischemia produces seemingly mild or transient symptoms. For transient ischemic …

Duration of Benefit and Risk of Dual Antiplatelet Therapy up to 72 Hours After Mild Ischemic Stroke and Transient Ischemic Attack

L Guan, S Han, SC Johnston, PM Bath, P Amarenco… - Neurology, 2024 - neurology.org
Background and Objectives Clopidogrel-aspirin initiated within 72 hours of symptom onset is
effective in patients with mild ischemic stroke or transient ischemic attack (TIA) in the …

Clopidogrel and Aspirin Initiated Between 24 to 72 Hours for Mild Ischemic Stroke: A Subgroup Analysis of the INSPIRES Randomized Clinical Trial

Y Liu, J Zhao, Y Gao, W Chen, SC Johnston… - JAMA Network …, 2024 - jamanetwork.com
Importance Prior trials showed that dual antiplatelet therapy could reduce the risk of early
new stroke in patients with acute mild ischemic stroke or transient ischemic attack (TIA) …

Beyond RCTs: Short-term dual antiplatelet therapy in secondary prevention of ischemic stroke and transient ischemic attack

E De Matteis, R Ornello, F De Santis… - European Stroke …, 2024 - journals.sagepub.com
Background and purpose: Randomized controlled trials (RCTs) proved the efficacy of short-
term dual antiplatelet therapy (DAPT) in secondary prevention of minor ischemic stroke or …

Optimal duration of dual antiplatelet therapy for minor stroke within 72 hours of symptom onset: a prospective cohort study

T Liu, Y Wang, K Zhang, H Fan, Y Li, J Ren… - Stroke and Vascular …, 2024 - svn.bmj.com
Objectives Despite the potential spillover effect, the optimal duration of dual antiplatelet
therapy for minor stroke within 72 hours of symptom onset is still uncertain. Methods Safety …

Ticagrelor versus clopidogrel in dual antiplatelet therapy after minor stroke or transient ischemic attack: an updated network meta-analysis

G Marinheiro, B Araújo, GA Monteiro, M Leite… - Journal of …, 2024 - Springer
Background Dual antiplatelet therapy (DAPT) with clopidogrel plus aspirin is a well-
established practice after a minor stroke or transient ischemic attack (TIA). However …

Combining Intravenous Thrombolysis and Dual Antiplatelet Treatment in Patients With Minor Ischemic Stroke: A Propensity Matched Analysis of the READAPT Study …

R Ornello, M Foschi, F De Santis, M Romoli… - Journal of the …, 2024 - ahajournals.org
Background The optimal treatment for acute minor ischemic stroke is still undefined. and
options include dual antiplatelet treatment (DAPT), intravenous thrombolysis (IVT), or their …

Dual Antiplatelet Therapy and Outcomes in Acute Mild to Moderate Stroke With Versus Without Large‐Artery Atherosclerosis Post Hoc Analysis of ATAMIS

Y Cui, QY Liu, HS Chen - Journal of the American Heart …, 2024 - ahajournals.org
Background We conducted a post hoc analysis of the ATAMIS (Antiplatelet Therapy in Acute
Mild to Moderate Ischemic Stroke) trial to investigate whether the priority of clopidogrel plus …